Järvi R, Helén P, Pelto-Huikko M, Hervonen A
Neurosci Lett. 1986 Jun 18;67(2):223-7. doi: 10.1016/0304-3940(86)90402-7.
The distribution of neuropeptide Y-like immunoreactivity (NPY-LI) was examined in the rat superior cervical and hypogastric ganglia. NPY-LI was localized in the majority of the sympathetic neurons, a few small granule-containing (SGC) cells and nerve terminals. Most of the NPY-immunoreactive sympathetic neurons were also tyrosine hydroxylase (TH)-immunoreactive but in hypogastric ganglia few neurons with NPY-LI were devoid of TH-immunoreactivity. Electron microscopically NPY-LI was found in the Golgi complexes of sympathetic neurons, in large cytoplasmic granules (100-150 nm in diameter) of the SGC cells and in large dense-cored vesicles (80-100 nm in diameter) of the nerve terminals. NPY-LI coexists mainly with noradrenaline in sympathetic neurons, and may have regulatory functions in sympathetic ganglia and in target organs.
研究了大鼠颈上神经节和腹下神经节中神经肽Y样免疫反应性（NPY-LI）的分布。NPY-LI定位于大多数交感神经元、少数含小颗粒（SGC）细胞和神经末梢中。大多数NPY免疫反应性交感神经元也呈酪氨酸羟化酶（TH）免疫反应性，但在腹下神经节中，少数具有NPY-LI的神经元缺乏TH免疫反应性。电镜下，NPY-LI存在于交感神经元的高尔基体复合物中、SGC细胞的大细胞质颗粒（直径100-150nm）中以及神经末梢的大致密核心囊泡（直径80-100nm）中。NPY-LI主要与去甲肾上腺素在交感神经元中共存，可能在交感神经节和靶器官中具有调节功能。
