Poston G J, Thomas A M, Macdonald D W, Karvounaris D, Henderson B L, George P, Lynn J A, Lavender J P
Nucl Med Commun. 1986 Apr;7(4):215-21. doi: 10.1097/00006231-198604000-00003.
The uptake of 131I-MIBG by medullary carcinoma of the thyroid was studied in six patients after total thyroidectomy in whom persistent raised plasma calcitonin levels were indicative of residual disease. The only patient in whom any activity in a possible metastasis was seen had by far the highest level of circulating calcitonin of the group and in contrast one patient with a presumptive metastatic deposit showed no uptake of MIBG into it. In conclusion the uptake of 131I-MIBG by medullary carcinoma of the thyroid is unreliable and unpredictable.
对6例甲状腺全切除术后持续性血浆降钙素水平升高提示有残留疾病的患者，研究了甲状腺髓样癌对131I-MIBG的摄取情况。在该组中，唯一在可能转移灶发现有任何放射性的患者，其循环降钙素水平是最高的；相反，1例推测有转移灶的患者，其转移灶未摄取MIBG。总之，甲状腺髓样癌对131I-MIBG的摄取是不可靠且无法预测的。
