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2型糖尿病患者血糖自我监测的依从性及其影响因素:一项基于腾讯TDF-I血糖监测平台的真实世界横断面研究

Compliance to self-monitoring of blood glucose among patients with type 2 diabetes mellitus and its influential factors: a real-world cross-sectional study based on the Tencent TDF-I blood glucose monitoring platform.

作者信息

Hu Zhi-De, Zhang Kai-Ping, Huang Ying, Zhu Shu

机构信息

Department of Laboratory Medicine, the General Hospital of Ji'nan Military Region, Ji'nan 250031, China.

AME College, AME Group, Flat/RM C 16F, Kings Wing Plaza 1, NO. 3 on Kwan Street, Shatin, NT, Hong Kong, China.

出版信息

Mhealth. 2017 Jun 27;3:25. doi: 10.21037/mhealth.2017.06.01. eCollection 2017.

Abstract

BACKGROUND

To investigate the compliance to self-monitoring of blood glucose (SMBG) among patients with type 2 diabetes mellitus (T2DM) and its influential factors.

METHODS

The real-world SMBG use over 90 days among 415 T2DM patients were recorded by using a blood glucose monitoring platform (TDF-I, Tencent, China). Clinical features including age, sex, duration of diabetes, insulin treatment or not, and use of oral antidiabetic drugs were collected. Poor compliance was defined as the average frequency of weekly SMBG use over 90 days was below the criteria established by the physicians, and otherwise the patients were regarded as with good compliance. Factors affecting the SMBG compliance were analyzed by using independent sample -test, Mann-Whitney U test, and multivariate logistic regression analysis.

RESULTS

Only 57.6% of patients in the study cohort had good compliance to SMBG. Multivariate logistic regression models showed that only the duration of T2DM and the use of oral antidiabetic agents were independently associated with SMBG compliance; more specifically, patients with longer course of disease had poorer SMBG compliance, and those had used oral antidiabetic agents had poorer SMBG compliance.

CONCLUSIONS

SMBG compliance in T2DM patients needs to be further improved. For patients with a longer course of disease and/or under oral antidiabetic medication, interventions such as patient education should be adopted to increase the SMBG compliance.

摘要

背景

调查2型糖尿病(T2DM)患者自我血糖监测(SMBG)的依从性及其影响因素。

方法

使用血糖监测平台(TDF-I,腾讯,中国)记录415例T2DM患者90天以上的实际SMBG使用情况。收集患者的临床特征,包括年龄、性别、糖尿病病程、是否接受胰岛素治疗以及口服降糖药的使用情况。依从性差定义为90天内每周SMBG使用的平均频率低于医生设定的标准,否则患者被视为依从性良好。采用独立样本t检验、曼-惠特尼U检验和多因素logistic回归分析影响SMBG依从性的因素。

结果

研究队列中仅有57.6%的患者对SMBG依从性良好。多因素logistic回归模型显示,仅T2DM病程和口服降糖药的使用与SMBG依从性独立相关;具体而言,病程较长的患者SMBG依从性较差,使用口服降糖药的患者SMBG依从性也较差。

结论

T2DM患者的SMBG依从性有待进一步提高。对于病程较长和/或接受口服降糖药治疗的患者,应采取患者教育等干预措施以提高SMBG依从性。

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