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围产期基孔肯雅病毒相关脑炎导致产后小头畸形和视神经萎缩。

Perinatal Chikungunya Virus-associated Encephalitis Leading to Postnatal-Onset Microcephaly and Optic Atrophy.

作者信息

Ramos Regina, Viana Rafaela, Brainer-Lima Alessandra, FloreÂncio Telma, Carvalho Maria Durce, van der Linden Vanessa, Amorim Antonio, Rocha Maria AÂngela, Medeiros Fabíola

机构信息

From the Department of Pediatric Infectious Diseases, Oswaldo Cruz Hospital, University of Pernambuco, Department of Neuropediatric, Oswaldo Cruz Hospital, University of Pernambuco, Department of Ophthalmology, Univision, and Department of Neuropediatric, Barão de Lucena Hospital, Recife, Brazil.

出版信息

Pediatr Infect Dis J. 2018 Jan;37(1):94-95. doi: 10.1097/INF.0000000000001690.

Abstract

Chikungunya virus is capable of affecting the nervous system of children and adults. We describe a case of sepsis and encephalitis triggered by this agent in a newborn whose mother developed symptoms of acute infection 2 days before delivery. Consequently, the infant had severe encephalitis that evolved with postnatal-onset microcephaly, bilateral optic atrophy, epilepsy and cerebral palsy.

摘要

基孔肯雅病毒能够影响儿童和成人的神经系统。我们描述了一例由该病原体引发的败血症和脑炎病例,患儿母亲在分娩前2天出现急性感染症状。因此,该婴儿患有严重脑炎,病情发展为产后小头畸形、双侧视神经萎缩、癫痫和脑瘫。

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