Han Mumei, Wang Liping, Li Siheng, Bai Liang, Zhou Yunjie, Sun Yue, Huang Hui, Li Hao, Liu Yang, Kang Zhenhui
Jiangsu Key Laboratory for Carbon-based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
Department of Mechanical Engineering, National University of Singapore, Singapore 117576, Singapore.
Talanta. 2017 Nov 1;174:265-273. doi: 10.1016/j.talanta.2017.05.067. Epub 2017 May 31.
The surface functionalization will introduce additional functional groups on carbon dots (CDs) surface and then enrich the properties of CDs. Here, we show the various surface functionalized CDs (-COOH, -OH, -SH, -NH, etc, named as NS-CDs) were synthesized with fascinating features, including high quantum efficiency (38.9%), long-term stability and good biocompatibility. Notably, it can serve as multifunction fluorescent probe in sensing system, including label-free detections in hydrogen peroxide (HO) with a wide linear range (1.20 × 10 - 8.80 × 10M) and a low limit of detection (LOD, 1.00 × 10M); and glutathione, covering a concentration range of 2.00 × 10 - 1.00 × 10M and LOD of 1.00 × 10M. In addition, the NS-CDs as fluorescent probe could selectively detect metal ions (such as, Hg, 1.00 × 10 - 1.50 × 10M, 1.00 × 10M), antibiotics (tetracycline, 1.00 ×10 - 2.50 × 10M, 1.00 ×10M) and toxic pollutant (nitrobenzene, 5.00 × 10 to 1.00 × 10gL, 5.00 × 10gL) with wide linear range and satisfactory detection limits.
表面功能化将在碳点（CDs）表面引入额外的官能团，进而丰富碳点的性质。在此，我们展示了合成的各种表面功能化碳点（-COOH、-OH、-SH、-NH等，命名为NS-CDs）具有迷人的特性，包括高量子效率（38.9%）、长期稳定性和良好的生物相容性。值得注意的是，它可以作为传感系统中的多功能荧光探针，包括对过氧化氢（HO）进行无标记检测，线性范围宽（1.20×10 - 8.80×10M）且检测限低（LOD，1.00×10M）；以及对谷胱甘肽的检测，浓度范围为2.00×10 - 1.00×10M，检测限为1.00×10M。此外，作为荧光探针的NS-CDs能够选择性地检测金属离子（如Hg，1.00×10 - 1.50×10M，1.00×10M）、抗生素（四环素，1.00×10 - 2.50×10M，1.00×10M）和有毒污染物（硝基苯，5.00×10至1.00×10gL，5.00×10gL），线性范围宽且检测限令人满意。
