Fontaine Frédéric-Georges, Stephan Douglas W
Department of Chemistry, Université Laval, Pavillon Alexandre-Vachon, 1045 avenue de la Médecine, Quebec City, Quebec, Canada G1V 0A6
Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada M5H 3H6
Philos Trans A Math Phys Eng Sci. 2017 Aug 28;375(2101). doi: 10.1098/rsta.2017.0004.
In this concept article, we consider the notion of 'frustrated Lewis pairs' (FLPs). While the original use of the term referred to steric inhibition of dative bond formation in a Lewis pair, work in the intervening decade demonstrates the limitation of this simplistic view. Analogies to known transition metal chemistry and the applications in other areas of chemistry are considered. In the light of these findings, we present reflections on the criteria for a definition of the term 'frustrated Lewis pair'. Segregation of the Lewis acid and base and the kinetic nature of FLP reactivity are discussed. We are led to the conclusion that, while an all-inclusive definition of FLP is challenging, the notion of 'FLP chemistry' is more readily recognized.This article is part of the themed issue 'Frustrated Lewis pair chemistry'.
在这篇概念文章中，我们探讨“受阻路易斯酸碱对”（FLPs）的概念。虽然该术语最初的用法指的是路易斯酸碱对中配位键形成的空间位阻抑制，但在随后十年的研究表明这种简单观点存在局限性。文中考虑了与已知过渡金属化学的类比以及在化学其他领域的应用。鉴于这些发现，我们对“受阻路易斯酸碱对”这一术语的定义标准进行了思考。讨论了路易斯酸和碱的分离以及FLP反应性的动力学性质。我们得出的结论是，虽然对FLP进行全面定义具有挑战性，但“FLP化学”的概念更容易被认可。本文是主题为“受阻路易斯酸碱对化学”的特刊的一部分。
