Han Tao, Yang Xiaodan, Xu Ying, Zheng Zhendong, Yan Ying, Wang Ning
Department of Oncology.
Department of Radiotherapy, General Hospital of Shenyang Military Region, Shenyang, China.
Onco Targets Ther. 2017 Jul 3;10:3277-3283. doi: 10.2147/OTT.S134290. eCollection 2017.
To explore the therapeutic value of 3-D printing template-assisted I-seed implantation in the treatment of malignant liver tumors.
Fifteen liver cancer patients with 47 total lesions were treated with 3-D printing template-assisted radioactive seed implantation (group A), and 25 liver-tumor patients with 66 total lesions were treated with I-seed implantation without a template auxiliary (group B). Operation time, in-hospital time, operation complications, dose distribution, and response rate (number) were compared between the two groups.
Shorter operation times and better dose distribution were observed in group A than in group B, and the differences were statistically significant. The response rate after 2 months was 86.7% (13 of 15) in group A and 84% (21 of 25) in group B; differences between the two groups were not significant.
Application of 3-D printing template-assisted radioactive seed implantation in the treatment of malignant liver tumors can help shorten operation time and optimize radiation-dose distribution, is worthy of further study, and has clinical significance.
探讨三维打印模板辅助碘籽源植入治疗肝脏恶性肿瘤的应用价值。
15例肝癌患者共47个病灶接受三维打印模板辅助放射性粒子植入治疗（A组），25例肝脏肿瘤患者共66个病灶接受无模板辅助碘籽源植入治疗（B组）。比较两组的手术时间、住院时间、手术并发症、剂量分布及有效率（例数）。
A组手术时间较B组短，剂量分布优于B组，差异有统计学意义。A组2个月后有效率为86.7%（15例中的13例），B组为84%（25例中的21例），两组差异无统计学意义。
三维打印模板辅助放射性粒子植入治疗肝脏恶性肿瘤有助于缩短手术时间、优化放射剂量分布，值得进一步研究，具有临床应用价值。
