Cengiz N, Gevrek T N, Sanyal R, Sanyal A
Department of Chemistry, Bogazici University, 34342 Bebek, Istanbul, Turkey.
Chem Commun (Camb). 2017 Aug 3;53(63):8894-8897. doi: 10.1039/c7cc02298k.
A combination of 'orthogonal' thiol-ene 'click' reactions is utilized for fabrication and functionalization of micro-patterned hydrogels. A furan-protected maleimide-containing parent copolymer is partially activated via the retro Diels-Alder reaction to obtain an 'orthogonally' functionalizable copolymer, where the different functional groups can be exploited for multi-functionalization or fabrication of functional hydrogels using combination of the nucleophilic and radical thiol-ene reactions.
利用“正交”硫醇-烯“点击”反应的组合来制备微图案水凝胶并对其进行功能化。一种含呋喃保护的马来酰亚胺的母体共聚物通过逆狄尔斯-阿尔德反应部分活化，以获得一种“正交”可功能化的共聚物，其中不同的官能团可用于多功能化或通过亲核硫醇-烯反应和自由基硫醇-烯反应的组合制备功能水凝胶。
