Turkheimer Eric, Beam Christopher R, Sundet Jon Martin, Tambs Kristian
University of Virginia, Charlottesville, VA, USA.
University of Southern California, Los Angeles, CA, USA.
Behav Genet. 2017 Sep;47(5):507-515. doi: 10.1007/s10519-017-9857-z. Epub 2017 Jul 25.
We examine a sample of Norwegian twin conscripts for evidence of an interaction between parental education and the heritability of general cognitive ability (GA). Ability scores were obtained on 1706 pairs of twins who were conscripted into the Norwegian Armed Forces between 1931and 1960. Education scores were available for mothers and fathers; the majority of the parents had less than a high school education. GA scores were heteroscadistic with respect to mid-parent education, with reduced variability at higher levels of education. Both MZ and DZ twin correlations for GA were linearly and negatively related to mid-parent education, DZ twins substantially more so. When the model was extended to an ACE model consisting of standardized positive ACE variance components, the modification appeared to disappear. Further analysis revealed that this occurred because the steep decline of DZ twin correlations with increasing mid-parent education resulted in a violation of the classical twin model for much of the parameter space. Other phenomena that might result in large declines in DZ twin correlations are considered, along with implications for other studies of socioeconomic interactions with the heritability of GA in European samples.
我们研究了一组挪威双胞胎应征者样本,以寻找父母教育程度与一般认知能力(GA)遗传力之间相互作用的证据。对1931年至1960年间应征加入挪威武装部队的1706对双胞胎进行了能力评分。可获得其父母的教育得分;大多数父母的教育程度低于高中。GA得分相对于父母平均教育程度呈异方差,在较高教育水平下变异性降低。GA的同卵双胞胎(MZ)和异卵双胞胎(DZ)相关性均与父母平均教育程度呈线性负相关,DZ双胞胎的相关性下降幅度更大。当模型扩展为由标准化正加性遗传(A)、共同环境(C)和独特环境(E)方差成分组成的ACE模型时,这种变化似乎消失了。进一步分析表明,出现这种情况是因为随着父母平均教育程度的增加,DZ双胞胎相关性急剧下降,导致在大部分参数空间中违反了经典双胞胎模型。我们还考虑了可能导致DZ双胞胎相关性大幅下降的其他现象,以及对欧洲样本中GA遗传力与社会经济相互作用的其他研究的影响。