自闭症谱系障碍焦虑症治疗（TAASD）研究：原理、设计与方法
The Treatment of Anxiety in Autism Spectrum Disorder (TAASD) Study: Rationale, Design and Methods.
作者信息
Kerns Connor M, Wood Jeffrey J, Kendall Philip C, Renno Patricia, Crawford Erika A, Mercado Rogelio J, Fujii Cori, Collier Amanda, Hoff Alexandra, Kagan Elana R, Small Brent J, Lewin Adam B, Storch Eric A
机构信息
Departments of Psychology and Community Health and Prevention, A.J. Drexel Autism Insitute, Drexel University, Philadelphia, PA, 19104, USA.
Adelphi University's Center for Health Innovation, Garden City, NY, USA.
出版信息
J Child Fam Stud. 2016 Jun;25(6):1889-1902. doi: 10.1007/s10826-016-0372-2. Epub 2016 Feb 6.
Abstract
This paper describes the rationale, design, and methods of the Treatment for Anxiety in Autism Spectrum Disorders study, a three-site randomized controlled trial investigating the relative efficacy of a modular CBT protocol for anxiety in ASD (Behavioral Interventions for Anxiety in Children with Autism) versus standard CBT for pediatric anxiety (the program) and a treatment-as-usual control. The trial is distinct in its scope, its direct comparison of active treatments for anxiety in ASD, and its comprehensive approach to assessing anxiety difficulties in youth with ASD. The trial will evaluate the relative benefits of CBT for children with ASD and investigate potential moderators (ASD severity, anxiety presentation, comorbidity) and mediators of treatment response, essential steps for future dissemination and implementation.
摘要
本文描述了“自闭症谱系障碍焦虑症治疗研究”的基本原理、设计和方法，这是一项三中心随机对照试验，旨在研究针对自闭症谱系障碍焦虑症的模块化认知行为疗法方案（针对自闭症儿童焦虑症的行为干预）相对于儿科焦虑症标准认知行为疗法（该方案）以及常规治疗对照的相对疗效。该试验在其规模、对自闭症谱系障碍焦虑症积极治疗的直接比较以及评估自闭症谱系障碍青少年焦虑问题的综合方法方面独具特色。该试验将评估认知行为疗法对自闭症谱系障碍儿童的相对益处，并调查潜在的调节因素（自闭症谱系障碍严重程度、焦虑表现、共病情况）和治疗反应的中介因素，这些都是未来推广和实施的关键步骤。
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