Shaibi Taher, Saadawi Walid K, Aghila H, Annajar Badereddin B
Zoology Department, Faculty of Science, University of Tripoli; National Centre for Disease Control, Ministry of Health, Tripoli, Libya.
National Centre for Disease Control, Ministry of Health, Tripoli, Libya.
J Vector Borne Dis. 2017 Apr-Jun;54(2):183-186.
BACKGROUND & OBJECTIVES: West Nile fever (WNF) is a mosquito-borne viral infection, circulated in natural cycles between birds and mosquitoes, particularly Culex species. It is transmitted to humans through mosquito bites, and causes a variety of clinical outcomes, ranging from asymptomatic or mild febrile illness to severe men in go encepha- litis with some fatalities observed in older or immunocompromised patients. West Nile virus (WNV) transmission is considerably influenced by environmental conditions; and abundance of avifauna and mosquitoes.There are very few reports on WNV exposure in individuals from Tripoli City in Libya. The main objective was to provide basic epidemiological information about the WNV seroprevalence in the human population of Tripoli.
A total of 400 serum samples were collected from persons (123 females, 277 males; age range: 15-78 yr) approaching the Tripoli Reference Laboratory for the purpose of obtaining health certificate; during the period from August to October 2013. The presence of WNV IgG antibodies was evaluated by a commercial kit based on WNV immunoglobulin G (IgG) enzyme-linked immunosorbent assay (ELISA).
It was observed that 2.75% (11/400) samples were found reactive in the WNV ELISA assay. This result suggests that WNV has a low prevalence in the study area.
INTERPRETATION & CONCLUSION: Seropositivity rates of WNV in Tripoli region of Libya were low. However, continu- ous monitoring of population is important to keep track of the disease prevalence, risk factors, reservoir hosts and vectors for better understaning of the disease epidemiology and designing appropriate control strategies.
西尼罗河热（WNF）是一种由蚊子传播的病毒感染，在鸟类和蚊子（特别是库蚊属）之间自然循环传播。它通过蚊子叮咬传播给人类，可导致多种临床结果，从无症状或轻度发热疾病到严重的脑膜炎，在老年人或免疫功能低下的患者中会出现一些死亡病例。西尼罗河病毒（WNV）的传播受到环境条件、鸟类和蚊子数量的显著影响。关于利比亚的黎波里市居民WNV暴露情况的报道非常少。主要目的是提供关于的黎波里市人群中WNV血清阳性率的基本流行病学信息。
2013年8月至10月期间，从前往的黎波里参考实验室获取健康证明的人员（123名女性，277名男性；年龄范围：15 - 78岁）中总共采集了400份血清样本。通过基于WNV免疫球蛋白G（IgG）酶联免疫吸附测定（ELISA）的商业试剂盒评估WNV IgG抗体的存在情况。
观察到在WNV ELISA检测中2.75%（11/400）的样本呈反应性。该结果表明WNV在研究区域的流行率较低。
利比亚的黎波里地区WNV的血清阳性率较低。然而，持续监测人群对于追踪疾病流行率、风险因素、储存宿主和传播媒介很重要，以便更好地了解疾病流行病学并设计适当的控制策略。
