[ABO血型与妊娠期糖尿病的关联]
[Association of abo blood groups with gestational diabetes mellitus].
作者信息
Huidobro M Andrea, Torres C Demetrio, Paredes Fabio
机构信息
Unidad de Epidemiología y Salud Pública, Facultad de Medicina, Universidad Católica del Maule, Talca, Chile.
División de Medicina Familiar y Salud Pública, Departamento de Salud Pública, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
出版信息
Rev Med Chil. 2017 Apr;145(4):431-435. doi: 10.4067/S0034-98872017000400002.
BACKGROUND
ABO and Rhesus blood systems are associated with type 2 Diabetes Mellitus (DM2). Gestational Diabetes (GDM) is a model to study DM.
AIM
To study the association between GDM and ABO and Rhesus groups.
MATERIAL AND METHODS
A retrospective cohort study was performed in 1,078 women who gave birth to a singleton in Talca Regional Hospital, Chile, during 2008. We analyzed personal, obstetric, medical data and ABO and Rh blood groups.
RESULTS
GDM was diagnosed in 6.6% of women. Age and body mass index were significantly associated with GDM. There were no differences in Rh blood groups (p = 0.604), while ABO groups were different between GDM and controls. B antigen was present in 3% of GDM women and in 10.8% of controls (p = 0.037), with an odds ratio of 0.25 after adjusting for other associated risk factors (p = 0.06).
CONCLUSIONS
ABO group is suggested as a possible protector marker for GDM.
背景
ABO和恒河猴血型系统与2型糖尿病（DM2）相关。妊娠期糖尿病（GDM）是研究糖尿病的一个模型。
目的
研究GDM与ABO和恒河猴血型组之间的关联。
材料与方法
对2008年在智利塔尔卡地区医院分娩单胎的1078名妇女进行了一项回顾性队列研究。我们分析了个人、产科、医学数据以及ABO和Rh血型。
结果
6.6%的妇女被诊断为GDM。年龄和体重指数与GDM显著相关。Rh血型组之间无差异（p = 0.604），而GDM组和对照组之间的ABO血型组不同。B抗原在3%的GDM妇女和10.8%的对照组妇女中存在（p = 0.037），在调整其他相关风险因素后，优势比为0.25（p = 0.06）。
结论
ABO血型组被认为是GDM的一种可能的保护标志物。
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