Kalmarzi R, Ataee P, Homagostar Gh, Tagik M, Ghaderi E, Kooti W
Cellular & Molecular Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Department of Pediatrics of Beast Hospital, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Allergol Immunopathol (Madr). 2018 Jan-Feb;46(1):45-57. doi: 10.1016/j.aller.2017.02.005. Epub 2017 Jul 24.
Food allergy refers to abnormal reactions of the body caused by an immune system response to food. This study was conducted aiming to investigate allergy to food allergens in children with food allergies.
This study was conducted as a cross-sectional one on 304 children aged six months to seven years with food allergies admitted to the tertiary referral hospital in Kurdistan Province - Iran, during 2014-2015. All the patients were examined for skin prick test using 49 allergens. Finally, the obtained data were analysed using SPSS15 and chi-square and t tests.
The highest percentage of occurrence of bump reaction (wheal) and redness (flare) was due to the consumption of fish, eggs, tomatoes, and cocoa. Moreover, the lowest rate of wheal and flare was caused by exposure to allergens like latex, tea, malt, and wheat flour. The reaction most created due to the consumption of foods was flare which was higher among under three-year-olds group (p<0.05), and between the sexes, girls showed the most common allergic reactions (p<0.05).
Since food allergy has a high prevalence in children, it should be considered with great interest. Considering that avoiding food allergens is the first step in the treatment of food allergies, the present study may be a useful guide in this regard.
食物过敏是指身体免疫系统对食物产生的异常反应。本研究旨在调查食物过敏儿童对食物过敏原的过敏情况。
本研究为横断面研究，于2014 - 2015年对伊朗库尔德斯坦省三级转诊医院收治的304名6个月至7岁的食物过敏儿童进行。所有患者均使用49种过敏原进行皮肤点刺试验。最后，使用SPSS15以及卡方检验和t检验对所得数据进行分析。
出现风团反应（风疹块）和红晕的最高比例是由于食用鱼类、蛋类、西红柿和可可。此外，风团和红晕的最低发生率是由接触乳胶、茶、麦芽和小麦粉等过敏原引起的。因食用食物产生的最常见反应是红晕，在3岁以下儿童组中更高（p<0.05），且在性别方面，女孩表现出最常见的过敏反应（p<0.05）。
由于食物过敏在儿童中患病率较高，应予以高度关注。鉴于避免食物过敏原是食物过敏治疗的第一步，本研究在这方面可能是一个有用的指南。
