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药物作为急性胰腺炎的病因

Medication as a Cause of Acute Pancreatitis.

作者信息

Ghatak Rupendra, Masso Lina, Kapadia Daniel, Kulairi Zain I

机构信息

Department of Internal Medicine, University of Medicine and Health Sciences, New York, NY, USA.

Department of Internal Medicine, Wayne State University, Crittenton Hospital, Rochester Hills, MI, USA.

出版信息

Am J Case Rep. 2017 Jul 28;18:839-841. doi: 10.12659/ajcr.903327.

DOI:10.12659/ajcr.903327
PMID:28751631
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5544058/
Abstract

BACKGROUND Acute pancreatitis is an inflammatory condition of the pancreas characterized clinically by epigastric abdominal pain and elevated levels of pancreatic enzymes in the blood. Drug-induced pancreatitis has recently gained more attention and as a result, physicians are screening more frequently for medications as a cause of acute pancreatitis. CASE REPORT We report the case of a 74-year-old man with a significant past medical history for coronary artery disease, sleep apnea, and gastroesophageal reflux disease who presented with epigastric pain radiating to the back. After a careful history was taken, it was found the patient recently started furosemide; therefore, a diagnosis of furosemide-induced acute pancreatitis was made. CONCLUSIONS Furosemide and other medications should be strongly considered in the differential diagnosis of patients presenting with acute pancreatitis.

摘要

背景

急性胰腺炎是胰腺的一种炎症性疾病,临床特征为上腹部疼痛和血液中胰腺酶水平升高。药物性胰腺炎最近受到了更多关注,因此,医生更频繁地筛查药物作为急性胰腺炎的病因。病例报告:我们报告一例74岁男性病例,他有冠状动脉疾病、睡眠呼吸暂停和胃食管反流病等重要既往病史,表现为上腹部疼痛并放射至背部。在仔细询问病史后,发现患者最近开始服用呋塞米;因此,诊断为呋塞米诱发的急性胰腺炎。结论:在对出现急性胰腺炎的患者进行鉴别诊断时,应高度考虑呋塞米和其他药物。

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[High-dose furosemide: a new cause of chronic pancreatitis?].
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