Allgulander C
Acta Psychiatr Scand. 1986 May;73(5):465-78. doi: 10.1111/j.1600-0447.1986.tb02713.x.
Sedative-hypnotic drug use and abuse increased in Europe after World War II and peaked about 1972. Clinical and follow-up descriptions of abusers support the concept of a psychiatric addiction syndrome, different from a low-dose withdrawal syndrome. Although these drugs may be prescribed unnecessarily, large portions of the general population with pathological psychic distress and insomnia do not receive psychotropic treatment, in spite of findings pointing to genetic and biochemical factors in the genesis of these. Research on underlying mechanisms and the rationale for maintenance therapy is needed.
二战后，欧洲镇静催眠药物的使用和滥用情况有所增加，并在1972年左右达到顶峰。对滥用者的临床及随访描述支持了一种精神成瘾综合征的概念，这与低剂量戒断综合征不同。尽管这些药物可能存在不必要的处方情况，但很大一部分患有病理性精神困扰和失眠的普通人群并未接受精神药物治疗，尽管有研究结果表明这些病症的发生存在遗传和生化因素。因此，需要对潜在机制及维持治疗的基本原理进行研究。
