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苯二氮䓬类药物是否被过度使用和滥用?

Are benzodiazepines overused and abused?

作者信息

Rickels K

出版信息

Br J Clin Pharmacol. 1981;11 Suppl 1(Suppl 1):71S-83S. doi: 10.1111/j.1365-2125.1981.tb01842.x.

Abstract

1 Drug use has to be viewed in the context of symptoms or illnesses for which they are prescribed. It is concluded that overall psychotropic drugs are used conservatively. 2 The benzodiazepines are safe drugs and in contrast with other centrally acting agents overuse will rarely have severe consequences. 3 Abrupt discontinuation may lead to temporary withdrawal reactions in patients who have been taking benzodiazepines regularly for 4 months or longer. Such reactions may occur more frequently in patients taking high doses.

摘要
  1. 药物使用必须结合其被处方治疗的症状或疾病来考量。得出的结论是,总体而言精神药物的使用较为保守。2. 苯二氮䓬类药物是安全的药物,与其他中枢作用药物相比,过度使用很少会产生严重后果。3. 突然停药可能会导致那些规律服用苯二氮䓬类药物达4个月或更长时间的患者出现暂时的戒断反应。此类反应在服用高剂量药物的患者中可能更频繁地发生。

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Are benzodiazepines overused and abused?苯二氮䓬类药物是否被过度使用和滥用?
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本文引用的文献

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The Drug Abuse Warning Network (DAWN) Program. Toxicologic verification of 1,008 emergency room 'mentions'.
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A study of prescribing patterns.一项处方模式研究。
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