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从反刍动物中分离出的弓形虫株的遗传多样性:系统评价。

Genetic diversity of Toxoplasma gondii isolates from ruminants: A systematic review.

机构信息

Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Mazandaran, Iran; Department of Parasitology and Mycology, School of Medicine, Mazandaran University of Medical Science, Sari, Mazandaran, Iran.

Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Mazandaran, Iran; Mazandaran University of Medical Sciences, Sari, Mazandaran, Iran.

出版信息

Int J Food Microbiol. 2017 Oct 3;258:38-49. doi: 10.1016/j.ijfoodmicro.2017.07.007. Epub 2017 Jul 15.

Abstract

Toxoplasma gondii is a protozoan capable of infecting all warm-blooded animals. This parasite has been classified into three major lineages. Our aim was to assess and compare the identified Types and genotypes in ruminants. From November 2014 to April 2015, four English language databases and four Persian databases that reported data on the T. gondii genotyping in ruminants were searched. Overall, typing results of the 250/307 T. gondii isolates in all animals showed that Type II was a predominant Type (81.4%). In addition, genotyping data from the 82/215 T. gondii isolates or strains indicated that atypical genotypes were predominant (38.13%). This systematic review has demonstrated a large degree of genetic diversity in some countries. However, in the new nomenclature of genotyping, there are atypical or exotic genotypes, such as Chinese 1, Types Br (I, II, III and IV), and Type 12. Further genotyping studies are required to corroborate the current results.

摘要

刚地弓形虫是一种能够感染所有温血动物的原生动物。该寄生虫已被分为三大谱系。我们的目的是评估和比较反刍动物中已鉴定的类型和基因型。从 2014 年 11 月至 2015 年 4 月,检索了 4 个英文数据库和 4 个波斯语数据库,这些数据库报告了有关反刍动物弓形虫基因分型的数据。总体而言,所有动物中 250/307 株弓形虫分离株的分型结果表明,II 型是主要类型(81.4%)。此外,82/215 株或株弓形虫分离株的基因分型数据表明,非典型基因型占优势(38.13%)。这项系统评价表明,一些国家存在很大程度的遗传多样性。然而,在新的基因分型命名法中,存在非典型或外来基因型,如中国 1 型、Br 型(I、II、III 和 IV 型)和 12 型。需要进一步的基因分型研究来证实目前的结果。

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