Gudala Kapil, Ghai Babita, Bansal Dipika
Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research, SAS Nagar (Mohali), India.
Department of Anesthesia and Intensive care, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Korean J Pain. 2017 Jul;30(3):197-206. doi: 10.3344/kjp.2017.30.3.197. Epub 2017 Jun 30.
Pain with neuropathic characteristics is generally more severe and associated with a lower quality of life compared to nociceptive pain (NcP). Short form of the Douleur Neuropathique en 4 Questions (S-DN4) is one of the most used and reliable screening questionnaires and is reported to have good diagnostic properties. This study was aimed to cross-culturally validate the Hindi version of the S-DN4 in patients with various chronic pain conditions.
The S-DN4 is already translated into the Hindi language by Mapi Research Trust. This study assessed the psychometric properties of the Hindi version of the S-DN4 including internal consistency and test-retest reliability after 3 days' post-baseline assessment. Diagnostic performance was also assessed.
One hundred sixty patients with chronic pain, 80 each in the neuropathic pain (NeP) present and NeP absent groups, were recruited. Patients with NeP present reported significantly higher S-DN4 scores in comparison to patients in the NeP absent group (mean (SD), 4.7 (1.7) vs. 1.8 (1.6), < 0.01). The S-DN4 was found to have an AUC of 0.88 with adequate internal consistency (Cronbach's α = 0.80) and a test-retest reliability (ICC = 0.92) with an optimal cut-off value of 3 (Youden's index = 0.66, sensitivity and specificity of 88.7% and 77.5%). The diagnostic concordance rate between clinician diagnosis and the S-DN4 questionnaire was 83.1% (kappa = 0.66).
Overall, the Hindi version of the S-DN4 has good internal consistency and test-retest reliability along with good diagnostic accuracy.
与伤害性疼痛（NcP）相比，具有神经病理性特征的疼痛通常更严重，且与较低的生活质量相关。《四问题神经病理性疼痛量表简版》（S-DN4）是最常用且可靠的筛查问卷之一，据报道具有良好的诊断性能。本研究旨在对S-DN4印地语版本在各种慢性疼痛患者中进行跨文化验证。
Mapi研究信托基金已将S-DN4翻译成印地语。本研究评估了S-DN4印地语版本的心理测量特性，包括基线评估后3天的内部一致性和重测信度。还评估了诊断性能。
招募了160名慢性疼痛患者，神经病理性疼痛（NeP）存在组和NeP不存在组各80名。与NeP不存在组的患者相比，NeP存在组的患者报告的S-DN4评分显著更高（均值（标准差），4.7（1.7）对1.8（1.6），<0.01）。发现S-DN4的曲线下面积为0.88，具有足够的内部一致性（Cronbach's α = 0.80）和重测信度（组内相关系数 = 0.92），最佳截断值为3（约登指数 = 0.66，灵敏度和特异度分别为88.7%和77.5%）。临床医生诊断与S-DN4问卷之间的诊断符合率为83.1%（kappa = 0.66）。
总体而言，S-DN4印地语版本具有良好的内部一致性、重测信度以及良好的诊断准确性。
