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多发性大动脉炎和家族性高胆固醇血症患者左心功能障碍的多模态评估。

Multimodality assessment of left ventricular dysfunction in Takayasu arteritis and familial hypercholesterolaemia.

机构信息

Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, 565-8565, Osaka, Japan.

Department of Molecular Innovation in Lipidology, National Cerebral and Cardiovascular Center, Suita, 565-8565, Osaka, Japan.

出版信息

ESC Heart Fail. 2017 Nov;4(4):655-659. doi: 10.1002/ehf2.12196. Epub 2017 Jul 31.

DOI:10.1002/ehf2.12196
PMID:28758710
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5695181/
Abstract

Although left ventricular (LV) systolic dysfunction in patients suffering from Takayasu arteritis (TA) has been reported, little is known regarding the development of heart failure in these patients. We report a novel finding of active TA and familial hypercholesterolaemia presenting with severe LV dysfunction through multimodality assessments of LV systolic dysfunction.

摘要

虽然已有研究报道了患有 Takayasu 动脉炎(TA)的患者存在左心室(LV)收缩功能障碍,但对于这些患者发生心力衰竭的情况知之甚少。我们报告了一例新的活动性 TA 和家族性高胆固醇血症病例,通过 LV 收缩功能障碍的多模式评估发现存在严重的 LV 功能障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f953/5695181/32b26f8819c4/EHF2-4-655-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f953/5695181/3158cd8f4769/EHF2-4-655-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f953/5695181/bbbd030012ee/EHF2-4-655-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f953/5695181/32b26f8819c4/EHF2-4-655-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f953/5695181/3158cd8f4769/EHF2-4-655-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f953/5695181/bbbd030012ee/EHF2-4-655-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f953/5695181/32b26f8819c4/EHF2-4-655-g003.jpg

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本文引用的文献

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Current Clinical Features of New Patients With Takayasu Arteritis Observed From Cross-Country Research in Japan: Age and Sex Specificity.日本跨国研究观察到的新 Takayasu 动脉炎患者的当前临床特征:年龄和性别特异性。
Circulation. 2015 Nov 3;132(18):1701-9. doi: 10.1161/CIRCULATIONAHA.114.012547. Epub 2015 Sep 9.
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Nonpharmacological lipoprotein apheresis reduces arterial inflammation in familial hypercholesterolemia.非药物性脂蛋白吸附疗法可降低家族性高胆固醇血症患者的动脉炎症。
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Findings of cardiac magnetic resonance imaging in asymptomatic myocardial ischemic disease in Takayasu arteritis.
Takayasu 动脉炎无症状性心肌缺血性疾病的心脏磁共振成像表现。
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Clin Rheumatol. 2010 Sep;29(9):973-81. doi: 10.1007/s10067-010-1496-1. Epub 2010 Jun 30.
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Takayasu arteritis: clinical features in 110 Mexican Mestizo patients and cardiovascular impact on survival and prognosis.高安动脉炎:110例墨西哥梅斯蒂索患者的临床特征及其对生存和预后的心血管影响
Clin Exp Rheumatol. 2008 May-Jun;26(3 Suppl 49):S9-15.
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Influences of hypercholesterolemia on red cell indices and erythrocyte sedimentation rate in elderly persons.高胆固醇血症对老年人红细胞指数及红细胞沉降率的影响。
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Differential hs-CRP reduction in patients with familial hypercholesterolemia treated with aggressive or conventional statin therapy.家族性高胆固醇血症患者接受强化或常规他汀类药物治疗后hs-CRP的差异降低。
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