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膜海鞘素，一种从冲绳海洋海绵膜海鞘属物种中提取的新型α-肾上腺素能受体阻断剂。

Hymenin, a novel alpha-adrenoreceptor blocking agent from the Okinawan marine sponge Hymeniacidon sp.

作者信息

Kobayashi J, Ohizumi Y, Nakamura H, Hirata Y, Wakamatsu K, Miyazawa T

出版信息

Experientia. 1986 Sep 15;42(9):1064-5. doi: 10.1007/BF01940735.

DOI:10.1007/BF01940735
PMID:2875898
Abstract

A novel bromine-containing alkaloid, hymenin, has been isolated from the Okinawan marine sponge Hymeniacidon sp. as a potent alpha-adrenoceptor blocking agent and its structure determined to be 1 on the basis of the spectral data.

摘要

从冲绳海洋海绵 Hymeniacidon sp. 中分离出一种新型含溴生物碱——海膜素，它是一种有效的α-肾上腺素能受体阻断剂，并根据光谱数据确定其结构为1。

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Pharmacological study on the venom of the marine snail Conus textile.
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Alpha-adrenoceptor blocking action of aaptamine, a novel marine natural product, in vascular smooth muscle.
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Ca-antagonistic substance from soft coral of the genus Sarcophyton.肉芝软珊瑚属软珊瑚中的钙拮抗物质。
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Bromopyrrole Alkaloids with the Inhibitory Effects against the Biofilm Formation of Gram Negative Bacteria.
具有抑制革兰氏阴性菌生物膜形成作用的溴代吡咯生物碱。
Mar Drugs. 2018 Jan 2;16(1):9. doi: 10.3390/md16010009.
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A novel antagonist of serotonergic receptors, hymenidin, isolated from the Okinawan marine sponge Hymeniacidon sp.
Experientia. 1986 Oct 15;42(10):1176-7. doi: 10.1007/BF01941300.
5
Alpha-adrenoceptor blocking action of hymenin, a novel marine alkaloid.新型海洋生物碱海膜素的α-肾上腺素能受体阻断作用
Experientia. 1988 Jan 15;44(1):86-7. doi: 10.1007/BF01960260.
6
A potent actomyosin ATPase activator from the Okinawan marine sponge Agelas cf. nemoechinata.一种来自冲绳海洋海绵Agelas cf. nemoechinata的强效肌动球蛋白ATP酶激活剂。
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Metabolism in porifera. III. Chemical patterns and the classification of the Desmospongiae.多孔动物的新陈代谢。III. 化学模式与寻常海绵纲的分类。
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