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肉芝软珊瑚属软珊瑚中的钙拮抗物质。

Ca-antagonistic substance from soft coral of the genus Sarcophyton.

作者信息

Kobayashi J, Ohizumi Y, Nakamura H, Yamakado T, Matsuzaki T, Hirata Y

出版信息

Experientia. 1983 Jan 15;39(1):67-9. doi: 10.1007/BF01960632.

DOI:10.1007/BF01960632
PMID:6130965
Abstract

A 14-membered ring diterpenoid named cembrane, possessing Ca-antagonistic action on the isolated rabbit aorta, has been isolated from a soft coral of the genus Sarcophyton, and its structure established by X-ray and spectroscopic data.

摘要

从肉芝软珊瑚属的一种软珊瑚中分离出一种名为西松烷的14元环二萜类化合物，它对离体兔主动脉具有钙拮抗作用，其结构已通过X射线和光谱数据确定。

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Ca-antagonistic substance from soft coral of the genus Sarcophyton.肉芝软珊瑚属软珊瑚中的钙拮抗物质。
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2
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J Am Chem Soc. 1977 Aug 17;99(17):5780-4. doi: 10.1021/ja00459a040.
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本文引用的文献

1
Pharmacological study on the venom of the marine snail Conus textile.
Toxicon. 1981;19(6):757-62. doi: 10.1016/0041-0101(81)90072-6.
2
Biphasic mechanical responses of the guinea-pig isolated ileum to the venom of the marine snail Conus striatus.豚鼠离体回肠对海蜗牛带纹芋螺毒液的双相机械反应。
Br J Pharmacol. 1981 Jul;73(3):583-5. doi: 10.1111/j.1476-5381.1981.tb16790.x.
3
Effect of venoms from Conidae on skeletal, cardiac and smooth muscles.
Toxicon. 1982;20(5):823-30. doi: 10.1016/0041-0101(82)90069-1.
4
二氯甲烷提取物对脂多糖诱导的小鼠核因子-κB和诱导型一氧化氮合酶表达的影响。
Vet World. 2019 Dec;12(12):1897-1902. doi: 10.14202/vetworld.2019.1897-1902. Epub 2019 Dec 3.
4
Chemical Diversity in Species Belonging to Soft Coral Genus and Its Impact on Biological Activity: A Review.化学多样性在软珊瑚属物种及其对生物活性的影响：综述。
Mar Drugs. 2020 Jan 6;18(1):41. doi: 10.3390/md18010041.
5
Screening of NO Inhibitor Release Activity from Soft Coral Extracts Origin Palu Bay, Central Sulawesi, Indonesia.对源自印度尼西亚中苏拉威西省帕卢湾的软珊瑚提取物的一氧化氮抑制剂释放活性进行筛选。
Antiinflamm Antiallergy Agents Med Chem. 2019;18(2):126-141. doi: 10.2174/1871523018666190222115034.
6
Cytotoxic cembranes from Indonesian specimens of the soft coral Nephthea sp.从印度尼西亚软珊瑚 Nephthea sp. 标本中分离得到细胞毒性的海松烷二萜
Mar Drugs. 2010 Jul 13;8(7):2142-52. doi: 10.3390/md8072142.
7
A novel antagonist of serotonergic receptors, hymenidin, isolated from the Okinawan marine sponge Hymeniacidon sp.
Experientia. 1986 Oct 15;42(10):1176-7. doi: 10.1007/BF01941300.
8
Hymenin, a novel alpha-adrenoreceptor blocking agent from the Okinawan marine sponge Hymeniacidon sp.膜海鞘素，一种从冲绳海洋海绵膜海鞘属物种中提取的新型α-肾上腺素能受体阻断剂。
Experientia. 1986 Sep 15;42(9):1064-5. doi: 10.1007/BF01940735.
Isolation of a cardiotonic glycoprotein, striatoxin, from the venom of the marine snail Conus Striatus.
Biochem Biophys Res Commun. 1982 Apr 29;105(4):1389-95. doi: 10.1016/0006-291x(82)90941-x.
5
The occurrence of arachidonic acid in the venom duct of the marine snail conus textile.海洋蜗牛织锦芋螺毒管中花生四烯酸的存在。
Experientia. 1982 Aug 15;38(8):897. doi: 10.1007/BF01953639.
6
Activation of vascular smooth muscle of rat aorta by noradrenaline and depolarization: two different mechanisms.去甲肾上腺素和去极化对大鼠主动脉血管平滑肌的激活：两种不同机制。
Pflugers Arch. 1971;330(1):74-89. doi: 10.1007/BF00588736.
7
Excitation-contraction coupling in rabbit aorta studied by the lanthanum method for measuring cellular calcium influx.用镧法测量细胞钙内流研究兔主动脉的兴奋-收缩偶联。
Circ Res. 1972 Jan;30(1):44-54. doi: 10.1161/01.res.30.1.44.
8
A study of compounds which inhibit vascular smooth muscle contraction.一项关于抑制血管平滑肌收缩的化合物的研究。
Eur J Pharmacol. 1973 Apr;22(1):75-82. doi: 10.1016/0014-2999(73)90186-6.
9
Effects of norepinephrine, dopamine and potassium on tension and 45Ca fluxes in canine and rabbit renal arteries.去甲肾上腺素、多巴胺和钾对犬和兔肾动脉张力及45钙通量的影响。
J Pharmacol Exp Ther. 1978 Nov;207(2):364-71.
10
Specific pharmacology of calcium in myocardium, cardiac pacemakers, and vascular smooth muscle.钙在心肌、心脏起搏器和血管平滑肌中的特殊药理学。
Annu Rev Pharmacol Toxicol. 1977;17:149-66. doi: 10.1146/annurev.pa.17.040177.001053.