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主动脉腔静脉压迫综合征:是时候重新审视某些教条了。

Aortocaval Compression Syndrome: Time to Revisit Certain Dogmas.

作者信息

Lee Allison J, Landau Ruth

机构信息

From the Department of Anesthesiology, Columbia University, New York, New York.

出版信息

Anesth Analg. 2017 Dec;125(6):1975-1985. doi: 10.1213/ANE.0000000000002313.

Abstract

More than 70 years ago, the phenomenon of "postural shock" in the supine position was described in healthy women in late pregnancy. Since then, avoidance of the supine position has become a key component of clinical practice. Indeed, performing pelvic tilt in mothers at term to avoid aortocaval compression is a universally adopted measure, particularly during cesarean delivery. The studies on which this practice is based are largely nonrandomized, utilized a mix of anesthetic techniques, and were conducted decades ago in the setting of avoidance of vasopressors. Recent evidence is beginning to refine our understanding of the physiologic consequences of aortocaval compression in the context of contemporary clinical practice. For example, magnetic resonance imaging of women at term in the supine and tilted positions has challenged the dogma that 15° of left tilt is sufficient to relieve inferior vena cava compression. A clinical investigation of healthy term women undergoing elective cesarean delivery with spinal anesthesia found no difference in neonatal acid-base status between women randomized to be either tilted to the left by 15° or to be in the supine position, if maternal systolic blood pressure is maintained at baseline with a crystalloid coload and prophylactic phenylephrine infusion. This review presents a fresh look at the decades of evidence surrounding this topic and proposes a reevaluation and appraisal of current guidelines regarding entrenched practices.

摘要

70多年前,晚期妊娠的健康女性中出现了仰卧位“姿势性休克”现象。从那时起,避免仰卧位已成为临床实践的关键组成部分。事实上,足月母亲进行骨盆倾斜以避免主动脉腔静脉受压是一项普遍采用的措施,尤其是在剖宫产期间。这种做法所依据的研究大多是非随机的,采用了多种麻醉技术,并且是在几十年前为避免使用血管升压药的背景下进行的。最近的证据开始完善我们对当代临床实践中主动脉腔静脉受压生理后果的理解。例如,对足月女性仰卧位和倾斜位的磁共振成像挑战了左倾15°足以缓解下腔静脉受压的教条。一项对接受脊髓麻醉的择期剖宫产足月健康女性的临床研究发现,如果通过晶体预负荷和预防性去氧肾上腺素输注将母亲的收缩压维持在基线水平,随机分为向左倾斜15°或仰卧位的女性之间新生儿酸碱状态没有差异。这篇综述重新审视了围绕该主题的数十年证据,并提议对有关既定做法的现行指南进行重新评估和评价。

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