Tarnow-Mordi W O, Fletcher M, Sutton P, Wilkinson A R
Lancet. 1986 Oct 18;2(8512):909-10. doi: 10.1016/s0140-6736(86)90424-1.
Data on routine humidifier settings used in respiratory support for newborn babies were obtained from 242 neonatal units in the British Isles. For each of the most commonly used humidifiers inspired gas humidity was measured under routine clinical conditions with an electronic hygrometer. Most endotracheally intubated babies breathe inspired gas of well below physiological humidity (44 mg H2O/l) and many below the minimum recommended for adults by the British Standards Institution (33 mg H2O/l). Inadequate humidification could contribute to several complications of artificial ventilation in newborn babies by inhibiting mucociliary clearance.
有关用于新生儿呼吸支持的常规加湿器设置的数据,是从英伦诸岛的242个新生儿重症监护病房获取的。对于每种最常用的加湿器,在常规临床条件下使用电子湿度计测量吸入气体的湿度。大多数经气管插管的婴儿吸入的气体湿度远低于生理湿度(44毫克水/升),许多婴儿低于英国标准协会为成年人推荐的最低湿度(33毫克水/升)。加湿不足可能会通过抑制黏液纤毛清除功能,导致新生儿人工通气的多种并发症。