Peterson Jeffrey R, Anderson John W, Blieden Lauren S, Chuang Alice Z, Feldman Robert M, Bell Nicholas P
*Ruiz Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Health Science Center at Houston (UTHealth) †Robert Cizik Eye Clinic, Houston, TX.
J Glaucoma. 2017 Sep;26(9):780-786. doi: 10.1097/IJG.0000000000000731.
To report long-term (>5 y) outcomes of plateau iris syndrome patients treated with argon laser peripheral iridoplasty (ALPI).
A retrospective chart review was performed on all patients with plateau iris syndrome treated with ALPI from 1996 to 2007. The study included 22 eyes from 22 patients with plateau iris after peripheral iridotomy that were followed for at least 1 year after ALPI. The primary outcome was incidence of needing any intraocular pressure (IOP)-lowering medications or surgery (either a filtering procedure or phacoemulsification). Demographic and baseline clinical data were summarized by mean (±SD) or frequency (percentage). Snellen best-corrected visual acuity was converted to logMAR. The paired t test was used to compare IOP changes, number of IOP-lowering medications, and best-corrected visual acuity from baseline to annual follow-up.
Mean follow-up was 76 months. Only 2 (9%) eyes maintained an IOP<21 mm Hg without requiring medication or surgery. Seventeen (77%) eyes underwent surgery at an average of 49.1±7.9 months after ALPI. Eight (36%) eyes underwent filtering surgery, and 9 (41%) eyes underwent phacoemulsification. Three months after cataract extraction, no eyes required IOP-lowering medication.
The beneficial effects of ALPI last for <4 years, with the majority of patients (77%) requiring surgery. Phacoemulsification alone was a successful treatment for plateau iris in our patient population.
报告接受氩激光周边虹膜成形术(ALPI)治疗的高原虹膜综合征患者的长期(>5年)预后。
对1996年至2007年期间接受ALPI治疗的所有高原虹膜综合征患者进行回顾性病历审查。该研究纳入了22例接受周边虹膜切开术后出现高原虹膜的患者的22只眼,这些眼在接受ALPI后至少随访1年。主要结局是需要使用任何降低眼压(IOP)的药物或进行手术(滤过手术或超声乳化白内障吸除术)的发生率。人口统计学和基线临床数据以均值(±标准差)或频率(百分比)进行总结。将Snellen最佳矫正视力转换为logMAR。采用配对t检验比较从基线到年度随访时的眼压变化、降低眼压药物的使用数量以及最佳矫正视力。
平均随访时间为76个月。只有2只眼(9%)眼压维持在<21 mmHg且无需药物或手术治疗。17只眼(77%)在接受ALPI后平均49.1±7.9个月接受了手术。8只眼(36%)接受了滤过手术,9只眼(41%)接受了超声乳化白内障吸除术。白内障摘除术后3个月,没有眼需要使用降低眼压的药物。
ALPI的有益效果持续时间不到4年,大多数患者(77%)需要手术治疗。在我们的患者群体中,单纯超声乳化白内障吸除术是治疗高原虹膜的成功方法。