Noya Belkisyolé Alarcón de, Pérez-Chacón Gladymar, Díaz-Bello Zoraida, Dickson Sonia, Muñoz-Calderón Arturo, Hernández Carlos, Pérez Yadira, Mauriello Luciano, Moronta Eyleen
Universidad Central de Venezuela, Facultad de Medicina, Instituto de Medicina Tropical, Sección de Inmunología, Caracas, Venezuela.
Universidad Central de Venezuela, Facultad de Medicina, Escuela de Medicina José María Vargas, Parasitología, Caracas, Venezuela.
Mem Inst Oswaldo Cruz. 2017 Aug;112(8):569-571. doi: 10.1590/0074-02760170009.
We describe the eleventh major outbreak of foodborne Trypanosoma cruzi transmission in urban Venezuela, including evidence for vertical transmission from the index case to her fetus. After confirming fetal death at 24 weeks of gestation, pregnancy interruption was performed. On direct examination of the amniotic fluid, trypomastigotes were detected. T. cruzi specific-polymerase chain reaction (PCR) also proved positive when examining autopsied fetal organs. Finally, microscopic fetal heart examination revealed amastigote nests. Acute orally transmitted Chagas disease can be life threatening or even fatal for pregnant women and unborn fetuses owing to vertical transmission. There is therefore an urgent need to improve national epidemiologic control measures.
我们描述了委内瑞拉城市中食源性克氏锥虫传播的第十一次重大疫情，包括从首例病例垂直传播至其胎儿的证据。在确认妊娠24周时胎儿死亡后，进行了引产。直接检查羊水时，检测到了锥鞭毛体。对尸检的胎儿器官进行检查时，克氏锥虫特异性聚合酶链反应（PCR）也呈阳性。最后，对胎儿心脏进行显微镜检查发现了无鞭毛体巢。由于垂直传播，急性经口传播的恰加斯病对孕妇和未出生胎儿可能危及生命甚至致命。因此，迫切需要改进国家流行病学控制措施。
