Muñoz M E, González J, Esteller A
Comp Biochem Physiol A Comp Physiol. 1986;85(1):67-71. doi: 10.1016/0300-9629(86)90463-9.
Bile and plasma levels of biliverdin and bilirubin, together with the hepatic biliverdin reductase and bilirubin UDP-glucuronosyl transferase activities, were studied in the rabbit. No biliverdin could be detected in the blood plasma. The bilirubin concentration in blood was 7.81 +/- 0.79 mumol/l. Biliverdin was the predominant pigment in bile (63%). Hepatic biliverdin reductase activity was 0.086 +/- 0.016 nmol/mg protein/hr. The synthesis of bilirubin was apparently limited by the enzyme activity. Most of the bilirubin in bile was conjugated (90%) with monoconjugates predominating (75%). Hepatic UDP-glucuronosyl transferase activity was 2.65 +/- 0.18 and 1.14 +/- 0.16 mumol/mg protein/hr with and without activation, respectively.
对家兔的胆汁和血浆中胆绿素和胆红素的水平，以及肝脏胆绿素还原酶和胆红素UDP - 葡萄糖醛酸基转移酶的活性进行了研究。血浆中未检测到胆绿素。血液中胆红素浓度为7.81±0.79μmol/l。胆绿素是胆汁中的主要色素（63%）。肝脏胆绿素还原酶活性为0.086±0.016 nmol/mg蛋白质/小时。胆红素的合成显然受该酶活性的限制。胆汁中的大部分胆红素是结合型的（90%），其中单结合物占主导（75%）。肝脏UDP - 葡萄糖醛酸基转移酶活性在有激活和无激活情况下分别为2.65±0.18和1.14±0.16μmol/mg蛋白质/小时。
