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葡萄糖给药对家兔胆红素排泄的影响。

Effect of glucose administration on bilirubin excretion in the rabbit.

作者信息

Muñoz M E, González J, Esteller A

出版信息

Experientia. 1987 Feb 15;43(2):166-8. doi: 10.1007/BF01942836.

DOI:10.1007/BF01942836
PMID:2949996
Abstract

The effect of i.v. infusion of glucose on the hepatic handling of bilirubin was examined in rabbits. A significant increase in the excretion of conjugated bilirubin into the bile was observed, accompanied by a decrease in bilirubinemia. Hepatic bilirubin concentrations were lowered and the UDP-glucose concentrations and liver UDP-glucuronosyl and UDP-glucosyl transferase activities increased.

摘要

在兔子身上研究了静脉输注葡萄糖对肝脏处理胆红素的影响。观察到胆汁中结合胆红素的排泄显著增加,同时胆红素血症有所降低。肝脏胆红素浓度降低,UDP-葡萄糖浓度以及肝脏UDP-葡糖醛酸基转移酶和UDP-葡萄糖基转移酶活性增加。

相似文献

1
Effect of glucose administration on bilirubin excretion in the rabbit.葡萄糖给药对家兔胆红素排泄的影响。
Experientia. 1987 Feb 15;43(2):166-8. doi: 10.1007/BF01942836.
2
Bile pigment formation and excretion in the rabbit.家兔体内胆汁色素的形成与排泄
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3
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本文引用的文献

1
Analysis of bilirubin and bilirubin mono- and di-conjugates. Determination of their relative amounts in biological samples.胆红素及胆红素单、双结合物的分析。测定其在生物样品中的相对含量。
Biochem J. 1980 Jan 1;185(1):115-28. doi: 10.1042/bj1850115.
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The effects of nutrition on unconjugated plasma bilirubin concentrations in squirrel monkeys.
Hepatology. 1984 May-Jun;4(3):454-60. doi: 10.1002/hep.1840040318.
4
Determination of bilirubin in liver homogenates and serum with diazotized p-iodoaniline.用重氮化对碘苯胺测定肝脏匀浆和血清中的胆红素。
Clin Chim Acta. 1971 Jan;31(1):109-18. doi: 10.1016/0009-8981(71)90367-6.
5
Assay and properties of dititonin-activated bilirubin uridine diphosphate glucuronyltransferase from rat liver.大鼠肝脏中地衣皂苷激活的胆红素尿苷二磷酸葡萄糖醛酸基转移酶的测定及性质
Biochem J. 1972 Sep;129(3):605-18. doi: 10.1042/bj1290605.
6
Role of glucose reabsorption from bile on hyperglycaemia-induced cholestasis in the rabbit.胆汁中葡萄糖重吸收在兔高血糖诱导胆汁淤积中的作用
J Hepatol. 1986;3(1):66-71. doi: 10.1016/s0168-8278(86)80147-7.
7
The measurement of bilirubin in liver.
Clin Chim Acta. 1975 Apr 16;60(2):215-8. doi: 10.1016/0009-8981(75)90128-x.
8
Comparison in different species of biliary bilirubin-IX alpha conjugates with the activities of hepatic and renal bilirubin-IX alpha-uridine diphosphate glycosyltransferases.不同物种中胆汁胆红素-IXα共轭物与肝脏和肾脏胆红素-IXα-尿苷二磷酸糖基转移酶活性的比较。
Biochem J. 1977 Jun 15;164(3):737-46. doi: 10.1042/bj1640737.