葡萄糖给药对家兔胆红素排泄的影响。
Effect of glucose administration on bilirubin excretion in the rabbit.
作者信息
Muñoz M E, González J, Esteller A
出版信息
Experientia. 1987 Feb 15;43(2):166-8. doi: 10.1007/BF01942836.
PMID:2949996
Abstract
The effect of i.v. infusion of glucose on the hepatic handling of bilirubin was examined in rabbits. A significant increase in the excretion of conjugated bilirubin into the bile was observed, accompanied by a decrease in bilirubinemia. Hepatic bilirubin concentrations were lowered and the UDP-glucose concentrations and liver UDP-glucuronosyl and UDP-glucosyl transferase activities increased.
摘要
在兔子身上研究了静脉输注葡萄糖对肝脏处理胆红素的影响。观察到胆汁中结合胆红素的排泄显著增加，同时胆红素血症有所降低。肝脏胆红素浓度降低，UDP-葡萄糖浓度以及肝脏UDP-葡糖醛酸基转移酶和UDP-葡萄糖基转移酶活性增加。
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