State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.
Laboratory of Environment and Biosafety, Research Institute of Southeast University in Suzhou, Suzhou, 215123, China.
Sci Rep. 2017 Aug 3;7(1):7255. doi: 10.1038/s41598-017-07267-9.
Here we report the vertical paper analytical devices (vPADs) fabricated using the principles of quilling and kirigami. What differentiates the vPADs from conventional paper microfluidic devices is that the paper substrate used to fabricate the device is placed vertically to the device plane. The fabrication of vPADs with high precision is instrument-free, requiring no photolithography, printing or heating. Two- and three-dimensional vPADs are fabricated for multiplex colorimetric assays of four biochemical indicators and automated enzyme-linked immunosorbent assay of human myoglobin, respectively.
在这里，我们报告了使用卷云和剪纸原理制造的垂直纸分析装置（vPAD）。与传统的纸微流控装置不同，用于制造该装置的纸基板垂直于装置平面放置。具有高精度的 vPAD 的制造是无仪器的，不需要光刻、打印或加热。分别为四种生化标志物的二维和三维 vPAD 设计了用于多重比色分析的多色比色分析，以及用于人肌红蛋白的自动化酶联免疫吸附测定。
