Bhattacharyya T K, Shandil M S
Classified Specialist (Obst & Gynae), Command Hospital (WC), Chandimandir, 134107.
Senior Advisor (Obst & Gynae), Military Hospital, Jalander.
Med J Armed Forces India. 1998 Jul;54(3):225-228. doi: 10.1016/S0377-1237(17)30549-X. Epub 2017 Jun 26.
154 patients requiring induction with unfavourable cervix at varying period of gestation were studied. Patients were distributed into two groups. 76 patients were induced with 0.5 mgm single dose intracervical application of Prostaglandin E2 gel and remaining 78 patients with Oxytocin and efficacy of the two methods of induction was compared. Labour was established within 24 hours in 71.4% of primigravidas and 91.7% of multigravidas in the prostaglandin treated group compared to 65.6% of primigravidas and 89.1% of multigravidas in the oxytocin group. The study found substantial improvement in cervical score 12 hours after application of intracervical prostaglandin E2 gel and decrease in Caesarean section rate with no major adverse effect to mother or neonate.
对154例在不同孕期需要引产且宫颈条件不佳的患者进行了研究。患者被分为两组。76例患者采用单次宫颈内应用0.5毫克前列腺素E2凝胶引产,其余78例患者采用催产素引产,并比较了两种引产方法的效果。前列腺素治疗组中,初产妇71.4%、经产妇91.7%在24小时内分娩,而催产素组初产妇为65.6%、经产妇为89.1%。研究发现,宫颈内应用前列腺素E2凝胶12小时后宫颈评分有显著改善,剖宫产率降低,且对母亲或新生儿无重大不良影响。