Centre for Tumour Biology, Barts and The London School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK.
Cell Stem Cell. 2017 Aug 3;21(2):159-160. doi: 10.1016/j.stem.2017.07.002.
Biliary ductal cells proliferate from the portal areas of chronically damaged livers, but their significance to regeneration has been controversial. A recent article in Nature by Raven et al. (2017) now shows that blocking hepatocyte replication is essential for the hepatic differentiation of ductular cells after liver damage.
胆管细胞从慢性损伤肝脏的门脉区域增殖，但它们对肝再生的意义一直存在争议。Raven 等人在《自然》杂志上的一篇最新文章（2017 年）表明，在肝损伤后，阻断肝细胞复制对于胆管细胞的肝分化是必需的。
