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螯合剂乙二胺四乙酸（EDTA）在埃及蟾蜍（Bufo regularis）急性镉中毒治疗中的应用、组织分布及一些血液参数

The use of the chelating agent EDTA in the treatment of acute cadmium toxicity, tissue distribution and some blood parameters in the Egyptian toad Bufo regularis.

作者信息

Hilmy A M, el-Domiaty N A, Daabees A Y, Abou Taleb E M

出版信息

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1986;85(1):67-74. doi: 10.1016/0742-8413(86)90053-8.

DOI:10.1016/0742-8413(86)90053-8
PMID:2877808
Abstract

Erythrocyte count, haemoglobin content, haematocrit value, erythrocyte sedimentation rate and cadmium accumulation in some organs and tissues were estimated in toads administered 6.2 mg Cd2+/kg i.m. for 4 days. EDTA therapy caused considerable decrease in all the blood parameters studied. A striking reduction in the cadmium content of all the organs and tissues studied except the kidneys was also observed after simultaneous treatment with EDTA.

摘要

对腹腔注射6.2毫克Cd2+/千克、持续4天的蟾蜍，测定其红细胞计数、血红蛋白含量、血细胞比容值、红细胞沉降率以及某些器官和组织中的镉蓄积量。乙二胺四乙酸（EDTA）疗法使所有研究的血液参数显著降低。同时用EDTA治疗后，除肾脏外，所有研究的器官和组织中的镉含量也显著降低。

相似文献

1
The use of the chelating agent EDTA in the treatment of acute cadmium toxicity, tissue distribution and some blood parameters in the Egyptian toad Bufo regularis.螯合剂乙二胺四乙酸（EDTA）在埃及蟾蜍（Bufo regularis）急性镉中毒治疗中的应用、组织分布及一些血液参数
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1986;85(1):67-74. doi: 10.1016/0742-8413(86)90053-8.
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Studies of Zn, Mg, Cu, Ca and Fe in cadmium poisoned toads before and after treatment with EDTA.
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Toxicity of cadmium administration to the toad and the treatment of its poisoning with EDTA.
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Effect of adriamycin on the morphology of the erythrocytes and blood parameters of the toad Bufo regularis.阿霉素对普通蟾蜍红细胞形态及血液参数的影响。
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