Zhang Jun, Han Fang
Department of Neurology, Peking University People's Hospital, 11, Xi Zhi Men Nan Da Jie, Xi Chen Qu, Beijing 100044, China.
Department of Respiratory Medicine, Peking University People's Hospital, 11, Xi Zhi Men Nan Da Jie, Xi Chen Qu, Beijing 100044, China.
Sleep Med Clin. 2017 Sep;12(3):323-330. doi: 10.1016/j.jsmc.2017.03.008. Epub 2017 May 13.
Narcolepsy represents the best understood disorder of excessive daytime sleepiness (EDS). EDS presents in 100% of patients with narcolepsy; it is usually the first and the most disabling symptom, which varies in aspects, such as onset age, severity, and clinical characteristics. Early recognition of this symptom leads to early diagnosis and intervention. A diagnosis of narcolepsy is based on clarifying EDS through history, subjective evaluation using questionnaires, and objective measurement, including nocturnal polysomnography followed by a daytime multiple sleep latency test. The therapeutic goal is to optimize control of EDS through wake-promoting medications and nonpharmacologic treatments.
发作性睡病是最被了解的过度日间嗜睡（EDS）障碍。100%的发作性睡病患者存在EDS；它通常是首发且最致残的症状，在发病年龄、严重程度和临床特征等方面存在差异。早期识别该症状可实现早期诊断和干预。发作性睡病的诊断基于通过病史、使用问卷进行主观评估以及客观测量（包括夜间多导睡眠图，随后进行日间多次睡眠潜伏期测试）来明确EDS。治疗目标是通过促醒药物和非药物治疗来优化对EDS的控制。
