Bhat Sushanth, Chokroverty Sudhansu
Division of Sleep Medicine, Department of Neuroscience, JFK Neuroscience Institute, Seton Hall University, 65 James Street, Edison, NJ 08818, USA.
Division of Sleep Medicine, Department of Neuroscience, JFK Neuroscience Institute, Seton Hall University, 65 James Street, Edison, NJ 08818, USA.
Sleep Med Clin. 2017 Sep;12(3):443-460. doi: 10.1016/j.jsmc.2017.03.017. Epub 2017 Jun 16.
Hypersomnia is a common complaint in many patients with neurodegenerative diseases and a major cause of decreased quality of life. This article discusses the prevalence and factors associated with hypersomnia in patients with a variety of neurodegenerative diseases affecting the central nervous system, including tauopathies, synucleinopathies, and other conditions. Common nocturnal sleep problems that may result in daytime hypersomnia are delineated. A clinical approach to hypersomnia in patients with neurodegenerative diseases, recommended diagnostic testing, and available treatment options are also discussed.
嗜睡症是许多神经退行性疾病患者常见的主诉，也是生活质量下降的主要原因。本文讨论了影响中枢神经系统的各种神经退行性疾病患者中嗜睡症的患病率及相关因素，包括tau蛋白病、α-突触核蛋白病及其他病症。文中还阐述了可能导致日间嗜睡的常见夜间睡眠问题。此外，还讨论了针对神经退行性疾病患者嗜睡症的临床处理方法、推荐的诊断测试及可用的治疗选择。
