Sánchez-Borrego Rafael, von Schacky Clemens, Osorio María José Alonso, Llaneza Plácido, Pinto Xavier, Losa Fernando, Navarro Mª Concepción, Lubián Daniel, Mendoza Nicolás
Clínica Diatros, Barcelona, Spain.
Preventive Cardiology, Medizinische Klinik I, Ludwig Maximilians-University of Munich, Germany.
Maturitas. 2017 Sep;103:71-77. doi: 10.1016/j.maturitas.2017.06.028. Epub 2017 Jun 24.
The consumption of long-chain omega-3 polyunsaturated fatty acids (LCO3-PUFAs) has shown a great variety of beneficial effects, including cardiovascular, metabolic and inflammatory effects, which make them interesting for the postmenopausal woman. Because LCO3-PUFAs could be effective and safe during this period, a panel of experts from the Spanish Menopause Society met to establish a set of recommendations for their use in postmenopausal women based on the best available evidence. The decrease in triglycerides is the most consistent effect observed with LCO3-PUFAs (at doses greater than 3g/day). In addition, LCO3-PUFAs have antiarrhythmic effects, reduce blood pressure, improve depressive and psychotic symptoms, and do not increase the risk of cancer. However, further studies are needed to confirm the benefit of LCO3-PUFAs in the relief of menopause symptoms and osteoporosis.
食用长链ω-3多不饱和脂肪酸(LCO3-PUFA)已显示出多种有益效果,包括心血管、代谢和炎症方面的作用,这使得它们对绝经后女性具有吸引力。由于LCO3-PUFA在此期间可能既有效又安全,西班牙绝经学会的一组专家开会,根据现有最佳证据制定了一套关于在绝经后女性中使用它们的建议。甘油三酯降低是LCO3-PUFA(剂量大于3克/天)观察到的最一致的效果。此外,LCO3-PUFA具有抗心律失常作用,可降低血压,改善抑郁和精神病症状,且不会增加患癌风险。然而,需要进一步研究来证实LCO3-PUFA在缓解更年期症状和骨质疏松症方面的益处。