酸浆皂苷K-Q，酸浆的七种新蔗糖酯。
Physakengoses K-Q, seven new sucrose esters from Physalis alkekengi var. franchetii.
作者信息
Zhang Chuan-Yang, Luo Jian-Guang, Liu Rui-Huan, Lin Ru, Yang Ming-Hua, Kong Ling-Yi
机构信息
State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, 210009, PR China.
State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, 210009, PR China.
出版信息
Carbohydr Res. 2017 Sep 8;449:120-124. doi: 10.1016/j.carres.2017.07.010. Epub 2017 Jul 28.
Seven sucrose esters, physakengoses K-Q (1-7) were isolated from the aerial parts of Physalis alkekengi var. franchetii. Their structures were elucidated on the basis of extensive spectroscopic analyses and chemical methods. These new compounds were tested for their antimicrobial abilities against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa and Escherichia coli. Among the isolated sucrose esters, compounds 1-5 showed potent antibacterial activity with MIC values ranging from 2.16 to 12.76 μg/mL.
从酸浆（Physalis alkekengi var. franchetii）地上部分分离得到七种蔗糖酯，即酸浆庚糖酯K - Q（1 - 7）。通过广泛的光谱分析和化学方法阐明了它们的结构。测试了这些新化合物对金黄色葡萄球菌、枯草芽孢杆菌、铜绿假单胞菌和大肠杆菌的抗菌能力。在所分离的蔗糖酯中，化合物1 - 5表现出较强的抗菌活性，其最低抑菌浓度（MIC）值在2.16至12.76μg/mL之间。
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