The Sansom Institute for Health Research, University of South Australia, Adelaide, Australia.
Department of Experimental Psychology, University of Oxford, Oxford, England, United Kingdom.
Cortex. 2018 Jul;104:154-162. doi: 10.1016/j.cortex.2017.06.024. Epub 2017 Jul 14.
Spatially-defined disruption of autonomic and sensory function has been identified in Complex Regional Pain Syndrome (CRPS). This study aimed to determine whether motor performance is also disrupted in a spatially-defined manner in people with CRPS.
Thirteen people with CRPS type 1 of the upper limb participated in two motor experiments. In Experiment 1 participants performed a circle drawing task that primarily tested motor accuracy. In Experiment 2 participants performed a button pressing task that tested motor co-ordination. In both experiments the motor tasks were performed with either hand (affected or healthy), and on either side of the body midline - that is, on the affected side of space or healthy side of space.
There was a main effect of both Limb and Side for the motor tasks. In Experiment 1, motor accuracy for the circle drawing task was poorer when participants used their affected hand than when they used their healthy one (p < .001), and when the task was performed on the affected side of their body midline than when it was performed on the healthy side (p < .001). In Experiment 2, motor co-ordination for the button pressing task was poorer when participants used their affected hand than when they used their healthy one (p < .001), and when the task was performed on the affected side of the midline (p < .001), as compared to the healthy side of the midline.
Unilateral CRPS is associated with a spatially-defined disruption of motor performance. Participants perform worse when the task is performed on the affected side of the body midline, regardless of whether they use their affected or healthy hand.
已在复杂性区域疼痛综合征（CRPS）中确定自主和感觉功能的空间破坏。本研究旨在确定 CRPS 患者的运动表现是否也以空间方式受到破坏。
13 名上肢 1 型 CRPS 患者参加了两项运动实验。在实验 1 中，参与者执行了主要测试运动准确性的圆形绘图任务。在实验 2 中，参与者执行了按钮按压任务，该任务测试运动协调性。在这两项实验中，运动任务均由手（患侧或健侧）和身体中线的任一侧执行，即空间的患侧或健康侧。
运动任务存在肢体和侧位的主要影响。在实验 1 中，参与者使用患手进行圆形绘图任务时的运动准确性要差于使用健手（p<.001），并且当任务在身体中线的患侧进行时，比在健康侧进行时（p<.001）差。在实验 2 中，参与者使用患手进行按钮按压任务时的运动协调性要差于使用健手（p<.001），并且当任务在中线的患侧进行时（p<.001），比在中线的健康侧进行时差。
单侧 CRPS 与运动表现的空间破坏有关。当任务在身体中线的患侧进行时，无论参与者使用患手还是健手，参与者的表现都会变差。
