Harvey S, Hall T R
Experientia. 1987 Jun 15;43(6):602-4. doi: 10.1007/BF02126345.
The inhibitory effects of pargyline and quipazine on chicken growth hormone secretion were overcome by passive immunoneutralization of endogenous somatostatin (SRIF)-14 or SRIF-28(1-14)-like immunoreactivity. Administration of the specific antisera to control birds pretreated with 0.9% NaCl elevated the basal plasma GH concentrations. These results suggest that peptides with SRIF-14 or SRIF-28(1-14)-like immunoreactivity tonically inhibit GH secretion and are at least partially responsible for the inhibitory effects of pargyline and quipazine on GH release in immature domestic fowl.
通过对内源性生长抑素（SRIF）-14或SRIF-28（1-14）样免疫反应性进行被动免疫中和，克服了帕吉林和喹哌嗪对鸡生长激素分泌的抑制作用。给用0.9%氯化钠预处理的对照鸡注射特异性抗血清，可提高基础血浆GH浓度。这些结果表明，具有SRIF-14或SRIF-28（1-14）样免疫反应性的肽持续抑制GH分泌，并且至少部分地导致了帕吉林和喹哌嗪对未成熟家禽GH释放的抑制作用。
