Harvey S, Hall T R
Gen Comp Endocrinol. 1987 Jan;65(1):111-6. doi: 10.1016/0016-6480(87)90229-2.
Immunoneutralization of endogenous somatostatin (SRIF)-28(1-14) by the intravenous or intramuscular administration of a specific antiserum promptly enhanced the growth hormone (GH) concentration in the plasma of 4 to 8-week-old cockerels. The magnitude of the GH response was related to the volume of antiserum administered. The release of GH from chicken pituitary glands incubated with intact hypothalami was increased in the presence of anti-SRIF-28(1-14). These results suggest that SRIF-28(1-14)-like peptides are physiologically involved in the control of GH secretion in chickens, in which they may tonically inhibit GH release.
通过静脉内或肌肉内注射特异性抗血清对内源性生长抑素（SRIF）-28(1-14)进行免疫中和，可迅速提高4至8周龄小公鸡血浆中的生长激素（GH）浓度。GH反应的幅度与抗血清的给药量有关。在抗SRIF-28(1-14)存在的情况下，与完整下丘脑一起孵育的鸡垂体释放的GH增加。这些结果表明，SRIF-28(1-14)样肽在生理上参与鸡GH分泌的控制，它们可能会持续性抑制GH的释放。
