Clapp Mark A, Bernstein Sarah N
Department of OBGYN, FND4, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA.
Harvard Medical School, Boston, MA, USA.
Curr Treat Options Cardiovasc Med. 2017 Sep;19(9):67. doi: 10.1007/s11936-017-0565-z.
All providers who care for reproductive-aged women with cardiac disease should assess these patients' desires and plans for pregnancy at every encounter. For those considering pregnancy, preconception counseling, often performed by a maternal-fetal medicine specialist, can help patients understand the potential implications of pregnancy on their health and estimate the risks of an adverse cardiac event prior to conceiving. There are cardiac conditions, such as pulmonary hypertension and aortic stenosis, in which pregnancy may be contraindicated given the high morbidity and mortality; there are tools available to help quantify a patient's risk. Furthermore, some cardiac lesions may be inherited, which may warrant parental testing or a discussion of strategies to reduce the risk of an affected child, such as the use of assisted reproductive technologies. Preconception counseling is also important to identify other maternal risk factors, such as obesity, hypertension, and tobacco use, which are associated with adverse pregnancy outcomes and develop a strategy to mitigate their potential risks, ideally before pregnancy. For women on medications for their heart disease or other comorbidities, a thorough review of these medications can potentially avoid an exposure to a teratogen during conception and pregnancy. Once pregnant, a patient's obstetrical provider and cardiologist should work together to outline a plan to monitor a patient's cardiac status as the normal physiologic changes of pregnancy, such as increased blood volume and cardiac output, may challenge a patient's functional status and increase the risk for an adverse outcome. Labor and delivery planning are essential to ensure patients with cardiac disease deliver at the appropriate hospital, equipped with the staff and resources to care for women with complex conditions. In summary, preconception counseling aims to stratify a patient's risk in pregnancy, inform patients of possible complications, and discuss strategies to best ensure a healthy mother and baby during pregnancy, labor, and delivery.
所有为患有心脏病的育龄妇女提供护理的医疗服务提供者,每次接诊时都应评估这些患者的妊娠意愿和计划。对于那些考虑怀孕的患者,通常由母胎医学专家进行的孕前咨询,可以帮助患者了解怀孕对其健康的潜在影响,并在受孕前估计发生不良心脏事件的风险。有些心脏疾病,如肺动脉高压和主动脉瓣狭窄,鉴于其高发病率和死亡率,怀孕可能是禁忌的;有一些工具可用于帮助量化患者的风险。此外,一些心脏病变可能是遗传性的,这可能需要对父母进行检测,或者讨论降低生出患病孩子风险的策略,比如使用辅助生殖技术。孕前咨询对于识别其他孕产妇风险因素也很重要,如肥胖、高血压和吸烟,这些因素与不良妊娠结局相关,并制定策略以减轻其潜在风险,最好在怀孕前进行。对于正在服用治疗心脏病或其他合并症药物的女性,对这些药物进行全面审查有可能避免在受孕和怀孕期间接触致畸剂。一旦怀孕,患者的产科医生和心脏病专家应共同制定计划,以监测患者的心脏状况,因为怀孕时正常的生理变化,如血容量和心输出量增加,可能会挑战患者的功能状态并增加不良结局的风险。分娩计划对于确保患有心脏病的患者在配备有照顾复杂病情女性的医护人员和资源的合适医院分娩至关重要。总之,孕前咨询旨在对患者的妊娠风险进行分层,告知患者可能出现的并发症,并讨论策略,以在孕期、分娩期和产褥期最好地确保母婴健康。