Afify Hesham, Kong Alexander, Bernal Jopher, Elgendy Islam Y
Department of Internal Medicine, University of Central Florida HCA Healthcare GME, Greater Orlando, FL, USA.
Department of Internal Medicine, University of Central Florida College of Medicine, Orlando, FL, USA.
Integr Blood Press Control. 2022 Apr 2;15:33-41. doi: 10.2147/IBPC.S242242. eCollection 2022.
Pulmonary hypertension (PH) is a heterogeneous disease characterized by an elevated mean pulmonary artery pressure of 20 mm Hg or above. PH is a prevalent condition among women of reproductive age and is linked with poor prognosis during pregnancy. Pregnancy is a stressful event and complicates the management and prognosis in patients with PH. In this review, we discuss the pathogenesis, clinical presentation as well as therapeutic options for PH during pregnancy. We also highlight knowledge gaps to guide future research.
肺动脉高压（PH）是一种异质性疾病，其特征为平均肺动脉压升高至20毫米汞柱及以上。PH在育龄女性中较为常见，且与孕期预后不良相关。怀孕是一个应激事件，会使PH患者的管理和预后变得复杂。在本综述中，我们讨论了孕期PH的发病机制、临床表现以及治疗选择。我们还强调了知识空白，以指导未来的研究。
