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基于Scheimpflug 原理的非接触式设备测量正常眼角膜眼生物力学数据的重复性。

Repeatability of ocular biomechanical data measurements with a Scheimpflug-based noncontact device on normal corneas.

机构信息

Department of Ophthalmology, University of Debrecen, Debrecen, Hungary.

出版信息

J Refract Surg. 2013 Aug;29(8):558-63. doi: 10.3928/1081597X-20130719-06.

Abstract

PURPOSE

To analyze the repeatability of a new device measuring ocular biomechanical properties, central corneal thickness (CCT), and intraocular pressure (IOP) and to investigate these parameters and their correlations in healthy eyes.

METHODS

Three consecutive measurements were performed on each eye using the CorVis ST device (Oculus Optikgeräte, Inc., Wetzler, Germany). Ten specific parameters, CCT, and IOP were measured. Biometric data were recorded with IOLMaster (Carl Zeiss Meditec, Jena, Germany).

RESULTS

This study comprised 75 eyes of 75 healthy volunteers (mean age: 61.24 ± 15.72 years). Mean IOP was 15.02 ± 2.90 mm Hg and mean CCT was 556.33 ± 33.13 μm. Intraclass correlation coefficient (ICC) was 0.865 for IOP and 0.970 for CCT, and coefficient of variation was 0.069 for IOP and 0.008 for CCT. ICC was 0.758 for maximum amplitude at highest concavity and 0.784 for first applanation time, and less than 0.6 for all other parameters. The device-specific data showed no significant relationship with age and axial length. Flattest and steepest keratometric values and IOP showed a significant correlation with the 10 device-specific parameters.

CONCLUSIONS

The CorVis ST showed high repeatability for only IOP and pachymetric values. Single measurements are not reliable for the 10 device-specific parameters. The device allows for conducting clinical examinations and screening for surgeries altering ocular biomechanical properties with some form of averaging of multiple measurements.

摘要

目的

分析一种新型测量眼生物力学特性、中央角膜厚度(CCT)和眼内压(IOP)的设备的重复性,并研究这些参数及其在健康眼中的相关性。

方法

使用 CorVis ST 设备(德国 Oculus Optikgeräte 公司)对每只眼进行 3 次连续测量。测量了 10 个特定参数、CCT 和 IOP。生物测量数据由 IOLMaster(卡尔蔡司 Meditec,耶拿,德国)记录。

结果

本研究纳入了 75 名健康志愿者的 75 只眼(平均年龄:61.24±15.72 岁)。平均 IOP 为 15.02±2.90mmHg,平均 CCT 为 556.33±33.13μm。IOP 的组内相关系数(ICC)为 0.865,CCT 的 ICC 为 0.970,IOP 的变异系数为 0.069,CCT 的变异系数为 0.008。最大凹陷处的最大振幅的 ICC 为 0.758,首次压平时间的 ICC 为 0.784,所有其他参数均低于 0.6。设备特定数据与年龄和眼轴长度无显著关系。最平坦和最陡峭的角膜曲率值和 IOP 与 10 个设备特定参数之间存在显著相关性。

结论

CorVis ST 仅对 IOP 和角膜厚度值显示出较高的重复性。单次测量对于 10 个设备特定参数不可靠。该设备允许进行临床检查和筛查,通过多次测量的某种平均方式,对改变眼生物力学特性的手术进行筛选。

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