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青少年重性抑郁障碍的冲动性:一项突尼斯的对比研究。

Impulsivity in adolescents with major depressive disorder: A comparative tunisian study.

机构信息

Department of Child Psychiatry, Hedi Chaker Hospital, Sfax,Tunisia; Faculty of Medecine South University, Sfax, Tunisia.

Department of Child Psychiatry, Hedi Chaker Hospital, Sfax,Tunisia; Faculty of Medecine South University, Sfax, Tunisia.

出版信息

Asian J Psychiatr. 2017 Aug;28:183-185. doi: 10.1016/j.ajp.2017.06.002. Epub 2017 Jun 7.

DOI:10.1016/j.ajp.2017.06.002
PMID:28784385
Abstract

BACKGROUND

The association between impulsivity and depressive disorders in adolescence has been little studied at the literature and in our country, yet impulsivity is a major risk factor for suicide. Thus we aimed on this study to evaluate impulsivity in 25 adolescents with Major Depressive Disorder MDD compared to a control sample and to analyze the correlations between impulsivity and clinical features of MDD.

METHODS

Employing a matched case-control design, participants included 25 adolescents with MDD and 75 controls. We have administered the Barratt Impulsivity Scale BIS-11 for the two groups to evaluate impulsivity. Semi structured interviews according DSM 5 criteria were conducted for adolescents with MDD. The Child Depressive Inventory CDI was used to measure depressive symptoms in the control sample.

RESULTS

Adolescents with MDD were more impulsive compared to controls according to the BIS-11 in its three domains: motor (24.96±6.26 against 20.6±4.84; p=0.000), attentional (20.88±5.03 against 16.64±3.2; p=0.000) and non planning (28.2±7.26 against 24.44±4.32; p=0.02). Impulsivity was not correlated with clinical features of MDD (suicide attempts, psychiatric comorbidities, antidepressant medication …).

CONCLUSION

Adolescents with MDD seem to be more impulsive than control subjects regardless their clinical features. Whether it is a specific characteristic or a symptom among others of MDD, impulsivity predicts health-related behaviors and associated damage that need to be detected and prevented in time.

摘要

背景

冲动与青少年抑郁障碍之间的关系在文献和我国研究中都很少被研究,然而冲动是自杀的一个主要危险因素。因此,我们旨在评估 25 名患有重性抑郁障碍(MDD)的青少年与对照组之间的冲动性,并分析冲动性与 MDD 临床特征之间的相关性。

方法

采用匹配病例对照设计,纳入 25 名患有 MDD 的青少年和 75 名对照。我们对两组青少年进行了巴瑞特冲动量表(BIS-11)评估以评估冲动性。根据 DSM 5 标准对患有 MDD 的青少年进行半结构化访谈。采用儿童抑郁量表(CDI)评估对照组的抑郁症状。

结果

根据 BIS-11 的三个维度:运动(24.96±6.26 对 20.6±4.84;p=0.000)、注意力(20.88±5.03 对 16.64±3.2;p=0.000)和非计划性(28.2±7.26 对 24.44±4.32;p=0.02),患有 MDD 的青少年比对照组更冲动。冲动性与 MDD 的临床特征(自杀企图、精神共病、抗抑郁药物……)无关。

结论

患有 MDD 的青少年似乎比对照组更冲动,无论其临床特征如何。冲动是 MDD 的一个特定特征还是其他症状之一,它预测了与健康相关的行为和相关损害,需要及时发现和预防。

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