Darlow Christopher A, Paidakakos Nikolaos, Sikander Murtuza, Atkins Bridget
Department of Infectious Diseases and Microbiology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Department of Neurosurgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
BMJ Case Rep. 2017 Aug 7;2017:bcr-2017-221260. doi: 10.1136/bcr-2017-221260.
We present a case of a 60-year-old woman with an invasive spinal infection with associated with a 15-year-old spinal fixation device and epidemiological contact with dogs. It was confirmed on blood culture and culture from pus from the epidural abscess and successfully treated using similar treatment as for a infection 6 weeks of intravenous flucloxacillin 2 g four times daily with a 6 week follow-on course of oral clindamycin 450 mg three times daily. This case represents the first reported deep abscess forming infection with this recently discovered organism. This case highlights that (1) has a potential for invasive zoonotic infection, (2) treatment as for appears adequate for resolution of the case, (3) the increased use of the matrix-assisted laser desorption/ionisation time-of-flight identification technique is leading to more specific identification of previously unrecognised organisms.
我们报告一例60岁女性,患有侵袭性脊柱感染,与一个使用了15年的脊柱固定装置有关,且有与狗的流行病学接触史。血液培养以及硬膜外脓肿脓液培养确诊了感染,采用与治疗感染相似的方法成功治疗,即静脉注射氟氯西林2克,每日4次,共6周,随后口服克林霉素450毫克,每日3次,共6周。该病例是首例报道的由这种最近发现的病原体引起的深部脓肿形成感染。该病例突出表明:(1) 有侵袭性人畜共患病感染的可能性;(2) 针对 的治疗似乎足以解决该病例;(3) 基质辅助激光解吸/电离飞行时间鉴定技术使用的增加正导致对以前未识别的病原体进行更特异性的鉴定。