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伴有……的脊柱感染

A spinal infection with .

作者信息

Darlow Christopher A, Paidakakos Nikolaos, Sikander Murtuza, Atkins Bridget

机构信息

Department of Infectious Diseases and Microbiology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Department of Neurosurgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

出版信息

BMJ Case Rep. 2017 Aug 7;2017:bcr-2017-221260. doi: 10.1136/bcr-2017-221260.

DOI:10.1136/bcr-2017-221260
PMID:28784907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5624009/
Abstract

We present a case of a 60-year-old woman with an invasive spinal infection with associated with a 15-year-old spinal fixation device and epidemiological contact with dogs. It was confirmed on blood culture and culture from pus from the epidural abscess and successfully treated using similar treatment as for a infection 6 weeks of intravenous flucloxacillin 2 g four times daily with a 6 week follow-on course of oral clindamycin 450 mg three times daily. This case represents the first reported deep abscess forming infection with this recently discovered organism. This case highlights that (1) has a potential for invasive zoonotic infection, (2) treatment as for appears adequate for resolution of the case, (3) the increased use of the matrix-assisted laser desorption/ionisation time-of-flight identification technique is leading to more specific identification of previously unrecognised organisms.

摘要

我们报告一例60岁女性,患有侵袭性脊柱感染,与一个使用了15年的脊柱固定装置有关,且有与狗的流行病学接触史。血液培养以及硬膜外脓肿脓液培养确诊了感染,采用与治疗感染相似的方法成功治疗,即静脉注射氟氯西林2克,每日4次,共6周,随后口服克林霉素450毫克,每日3次,共6周。该病例是首例报道的由这种最近发现的病原体引起的深部脓肿形成感染。该病例突出表明:(1) 有侵袭性人畜共患病感染的可能性;(2) 针对 的治疗似乎足以解决该病例;(3) 基质辅助激光解吸/电离飞行时间鉴定技术使用的增加正导致对以前未识别的病原体进行更特异性的鉴定。

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Diagn Microbiol Infect Dis. 2016 Aug;85(4):471-6. doi: 10.1016/j.diagmicrobio.2016.05.008. Epub 2016 May 12.
2
Staphylococcus pseudintermedius can be misdiagnosed as Staphylococcus aureus in humans with dog bite wounds.在被狗咬伤的人类患者中,中间型假葡萄球菌可能会被误诊为金黄色葡萄球菌。
Eur J Clin Microbiol Infect Dis. 2015 Apr;34(4):839-44. doi: 10.1007/s10096-014-2300-y. Epub 2014 Dec 23.
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Methicillin-resistant Staphylococcus pseudintermedius infection in a bone marrow transplant recipient.耐甲氧西林中间葡萄球菌感染骨髓移植受者。
J Clin Microbiol. 2013 May;51(5):1636-8. doi: 10.1128/JCM.03310-12. Epub 2013 Mar 13.
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