Shaqdan Khalid W, Kambadakone Avinash R, Hahn Peter, Sahani Dushyant V
From the Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
J Comput Assist Tomogr. 2018 Jan/Feb;42(1):124-132. doi: 10.1097/RCT.0000000000000656.
The aim of this study was to investigate the diagnostic performance of abdominopelvic computed tomography (CT) images reconstructed using filtered back projection (FBP) and iterative reconstruction (IR) algorithms in morbidly and super obese patients.
One hundred eighty-seven abdominopelvic CT examinations in portal venous phase were performed between February 2015 and February 2016 in 182 patients (mean age = 52 years, mean body mass index = 45.5). One hundred fourteen of 187 examinations were reconstructed using IR and 73 examinations were processed using FBP. Patients were further stratified based on body mass index. Sixty CT scans were reviewed by a single reader for image quality, image noise, and artifacts. Objective noise and attenuation were also determined. Size-specific dose estimate and CT dose index volume were compared and statistically analyzed.
A diagnostic interpretation was rendered for all 187 examinations. A single-reader review of 60 cases showed greater diagnostic acceptability for IR when compared with FBP (image quality = 4.2 and 3.8 [P = 0.035], noise = 1.5 and 1.6 [P = 0.692], artifact = 1.4 and 1.5 [P = 0.759], respectively). For all examinations, the IR group had lower objective image noise (IR = 9.3 and FBP = 14.3; P < 0.001) and higher contrast-to-noise ratio (IR = 17.2 and FBP = 11.7; P < 0.001) without increase in radiation dose (size-specific dose estimate [IR = 15.1, FBP = 16.5 mGy; P = 0.045] and CT dose index volume [IR = 17.6, FBP = 18 mGy; P = 0.62]).
In morbidly and super obese patients, diagnostic quality images could be reliably generated with minimal artifacts and noise using newer generation scanners integrated with IR without increasing radiation dose.
本研究旨在调查使用滤波反投影(FBP)和迭代重建(IR)算法重建的腹部盆腔计算机断层扫描(CT)图像在病态肥胖和超级肥胖患者中的诊断性能。
2015年2月至2016年2月期间,对182例患者(平均年龄 = 52岁,平均体重指数 = 45.5)进行了187次门静脉期腹部盆腔CT检查。187次检查中的114次使用IR重建,73次检查使用FBP处理。患者根据体重指数进一步分层。由一名阅片者对60例CT扫描进行图像质量、图像噪声和伪影的评估。还测定了客观噪声和衰减。比较并统计分析了特定尺寸剂量估计值和CT剂量指数容积。
对所有187次检查均做出了诊断解释。对60例病例的单阅片者评估显示,与FBP相比,IR的诊断可接受性更高(图像质量分别为4.2和3.8 [P = 0.035],噪声分别为1.5和1.6 [P = 0.692],伪影分别为1.4和1.5 [P = 0.759])。对于所有检查,IR组的客观图像噪声更低(IR = 9.3,FBP = 14.3;P < 0.001),对比噪声比更高(IR = 17.2,FBP = 11.7;P < 0.001)且辐射剂量未增加(特定尺寸剂量估计值[IR = 15.1,FBP = 16.5 mGy;P = 0.045]和CT剂量指数容积[IR = 17.6,FBP = 18 mGy;P = 0.62])。
在病态肥胖和超级肥胖患者中,使用集成了IR的新一代扫描仪,可在不增加辐射剂量的情况下,以最小的伪影和噪声可靠地生成诊断质量的图像。