State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China.
Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12692-12696. doi: 10.1002/anie.201706401. Epub 2017 Aug 31.
A novel palladium-catalyzed intermolecular oxidative fluorocarbonylation of alkenes has been developed, in which employment of a cooperative process with electrophilic ArIF -meidated alkenes activation and palladium-catalyzed carbonylation is crucial for the successful catalytic transformation. The current transformation presents the first convenient method to generate β-fluorinated carboxylic acid derivatives under mild reaction conditions from simple alkenes with excellent regioselectivity.
一种新型的钯催化的烯烃分子间氧化氟羰基化反应已经被开发出来，其中采用协同过程，即亲电的 ArIF-介导的烯烃活化和钯催化的羰基化，对于成功的催化转化至关重要。目前的转化方法为在温和的反应条件下，从简单的烯烃出发，以优异的区域选择性生成β-氟化羧酸衍生物提供了第一个方便的方法。
