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[药房中癌症化疗药物的安全处理(制剂、运输与安全存放)]

[Safe Handling of Cancer Chemotherapy Drugs in Pharmacy(Preparations, Transport and Safe Deposit)].

作者信息

Nomura Hisanaga

机构信息

Dept. of Pharmacy, National Cancer Center Hospital East.

出版信息

Gan To Kagaku Ryoho. 2017 Jul;44(7):554-557.

Abstract

Recently, 1 out of 2 people are diagnosed as cancer, the number of patients who are given chemotherapy increases year by year. As a result, amount of anticancer drugs used also increases. Anticancer drug preparation work is one of pharmacist work. In many hospital, pharmacists prepare anticancer drugs at pharmacy. However, it is enough to take steps to exposure measures at all facilities. According to the United States Pharmacopeial(USP)and the handling standards of hazardous and drugs, there are 3 levels, the first level(safety cabinet), the second level(anticancer agent preparation room in pharmacy) and supplemental engineering control(CSTD). It is described that exposure control should be carried out with exposure control. Strict standards are stated for each. In Japan, efforts to cope with exposure gradually are spreading gradually after exposure GL is published. Proper preparation environment/equipment, personal protective equipment, procedures and supplementary equipment are required for adequate exposure control measures. Also, it is important for exposure control to focus not only on anticancer drug preparation work but also on transportation and storage. This time, we describe exposure preparation, transportation to storage from dispensing.

摘要

最近,每两个人中就有一人被诊断患有癌症,接受化疗的患者数量逐年增加。因此,抗癌药物的使用量也在增加。抗癌药物配制工作是药剂师工作之一。在许多医院,药剂师在药房配制抗癌药物。然而,并非所有机构都采取了足够的接触防护措施。根据美国药典(USP)以及危险和药品的处理标准,有三个级别,第一级(安全柜)、第二级(药房中的抗癌剂配制室)和补充工程控制(CSTD)。其中描述了应通过接触控制来进行暴露控制。对每个级别都规定了严格的标准。在日本,自接触GL发布后,应对接触的措施正在逐渐推广。为了采取充分的接触控制措施,需要适当的配制环境/设备、个人防护设备、程序和辅助设备。此外,对于接触控制而言,不仅要关注抗癌药物的配制工作,还要关注运输和储存,这一点很重要。此次,我们将描述从调配到储存的接触准备及运输过程。

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