结核病诊断技术的最新进展
RECENT ADVANCES IN TUBERCULOSIS DIAGNOSTIC TECHNIQUES.
作者信息
Menon P K, Kapila K, Ohri V C
机构信息
Reader, Department of Microbiology, Armed Forces Medical College, Pune 411 040.
Classified Specialist (Pathology and Microbiology), Command Hospital (NC), C/o 56 APO.
出版信息
Med J Armed Forces India. 2000 Apr;56(2):143-148. doi: 10.1016/S0377-1237(17)30131-4. Epub 2017 Jun 10.
Tuberculosis is re-emerging as an important cause of morbidity and mortality in man. This article outlines current strategies available for the diagnosis of tuberculosis, and its applicability. Fluorescent staming, modified culture methods, antigen detection, ELISA based assays against various antigen preparation and recent advances in molecular techniques have been outlined. Present strategies being developed at Armed Forces Medical College for the early diagnosis, speciation, antibiotic sensitivity testing and epidemiologic testing have also been alluded to.
结核病再度成为人类发病和死亡的重要原因。本文概述了目前可用于结核病诊断的策略及其适用性。文中概述了荧光染色、改良培养方法、抗原检测、针对各种抗原制剂的基于酶联免疫吸附测定（ELISA）的检测方法以及分子技术的最新进展。还提及了武装部队医学院正在研发的用于早期诊断、菌种鉴定、抗生素敏感性检测和流行病学检测的当前策略。
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