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生活质量与尿石症:患者报告结局测量信息系统(PROMIS)

Quality of life and urolithiasis: the patient - reported outcomes measurement information system (PROMIS).

作者信息

Patel Nishant, Brown Robert D, Sarkissian Carl, De Shubha, Monga Manoj

机构信息

Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

出版信息

Int Braz J Urol. 2017 Sep-Oct;43(5):880-886. doi: 10.1590/S1677-5538.IBJU.2016.0649.

Abstract

BACKGROUND

With a high rate of recurrence, urolithiasis is a chronic disease that impacts quality of life. The Patient Reported Outcomes Measurement Information System is an NIH validated questionnaire to assess patient quality of life. We evaluated the impact of urolithiasis on quality of life using the NIH-sponsored PROMIS-43 questionnaire.

MATERIALS AND METHODS

Patients reporting to the kidney stone clinic were interviewed to collect information on stone history and demographic information and were asked to complete the PROMIS-43 questionnaire. Quality of life scores were analyzed using gender and age matched groups for the general US population. Statistical comparisons were made based on demographic information and patient stone history. Statistical significance was P<0.05.

RESULTS

103 patients completed the survey. 36% of respondents were male, the average age of the group was 52 years old, with 58% primary income earners, and 35% primary caregivers. 7% had never passed a stone or had a procedure while 17% passed 10 or more stones in their lifetime. Overall, pain and physical function were worse in patients with urolithiasis. Primary income earners had better quality of life while primary caregivers and those with other chronic medical conditions were worse. Patients on dietary and medical therapy had better quality of life scores.

CONCLUSIONS

Urolithiasis patients subjectively have worse pain and physical function than the general population. The impact of pain on quality of life was greatest in those patients who had more stone episodes, underscoring the importance of preventive measures. Stone prevention measures improve quality of life.

摘要

背景

尿石症是一种复发率高的慢性疾病,会影响生活质量。患者报告结局测量信息系统是美国国立卫生研究院(NIH)验证的用于评估患者生活质量的问卷。我们使用NIH赞助的PROMIS - 43问卷评估了尿石症对生活质量的影响。

材料与方法

对到肾结石门诊就诊的患者进行访谈,收集结石病史和人口统计学信息,并要求他们完成PROMIS - 43问卷。使用与美国总体人群性别和年龄匹配的组分析生活质量得分。根据人口统计学信息和患者结石病史进行统计比较。统计学显著性为P<0.05。

结果

103名患者完成了调查。36%的受访者为男性,该组的平均年龄为52岁,58%为主要收入者,35%为主要照顾者。7%的人从未排出过结石或接受过相关治疗,而17%的人一生中排出过10颗或更多结石。总体而言,尿石症患者的疼痛和身体功能较差。主要收入者的生活质量较好,而主要照顾者和患有其他慢性疾病的人生活质量较差。接受饮食和药物治疗的患者生活质量得分较高。

结论

尿石症患者主观上的疼痛和身体功能比一般人群更差。疼痛对生活质量的影响在结石发作次数较多的患者中最大,这突出了预防措施的重要性。结石预防措施可改善生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dcf/5678519/88b8cbc18c6c/1677-5538-ibju-43-05-0880-gf01.jpg

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