重现性“危机”：对复制危机的反应不应扼杀创新。
The reproducibility "crisis": Reaction to replication crisis should not stifle innovation.
机构信息
London, UK.
出版信息
EMBO Rep. 2017 Sep;18(9):1493-1496. doi: 10.15252/embr.201744876. Epub 2017 Aug 9.
Abstract
The purported reproducibility crisis has triggered both studies to analyze the problem and proposals to address it. However, it is important to not stifle exploratory, cutting‐edge research. [Image: see text]
摘要
所谓的可重复性危机既引发了分析这一问题的研究，也促成了应对这一问题的建议。但是，必须注意不要扼杀探索性的前沿研究。[图片：见正文]
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2
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3
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4
Exotic mice as models for aging research: polemic and prospectus.作为衰老研究模型的实验小鼠：争议与展望
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