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精神分裂症患者失配负波评估中偏差可预测性的数据。

Data on deviance predictability in the assessment of mismatch negativity in patients with schizophrenia.

作者信息

Horacek Magdalena, Kärgel Christian, Scherbaum Norbert, Müller Bernhard W

机构信息

Department of Psychiatry and Psychotherapy, LVR-Hospital Essen, Faculty of Medicine, University of Duisburg-Essen, Virchowstrasse 174, 45147 Essen, Germany.

Department of Addiction Medicine and Addictive Behavior, LVR-Hospital Essen, Faculty of Medicine, University of Duisburg-Essen, Virchowstrasse 174, 45147 Essen, Germany.

出版信息

Data Brief. 2016 Mar 17;7:763-769. doi: 10.1016/j.dib.2016.03.045. eCollection 2016 Jun.

DOI:10.1016/j.dib.2016.03.045
PMID:28795117
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5540674/
Abstract

We investigated the MMN at electrode Fz to 12% temporally predictable or unpredictable duration decrement deviant stimuli in 29 healthy controls and 31 schizophrenia patients. With a stimulus onset asynchronicity of 500 ms in the regular predictable condition, a deviant occurred every 4 s while it varied randomly in the unpredictable condition. Here we report detailed data tables and multivariate analysis of variance results (MANOVA) on MMN, P3a and standard ERP data including details on follow-up analyses. An extended figure shows MMN difference curves and averages to standard and deviant stimuli in both experimental conditions and subject groups.

摘要

我们在29名健康对照者和31名精神分裂症患者中,研究了电极Fz处对12%时间上可预测或不可预测的时长递减偏差刺激的失匹配负波(MMN)。在常规可预测条件下,刺激起始异步性为500毫秒,每4秒出现一次偏差刺激,而在不可预测条件下,偏差刺激随机出现。在此,我们报告关于MMN、P3a和标准事件相关电位(ERP)数据的详细数据表及多变量方差分析结果(MANOVA),包括后续分析的详细信息。一张扩展图展示了两种实验条件和受试者组中,MMN对标准刺激和偏差刺激的差异曲线及平均值。

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本文引用的文献

1
Event-related potentials in clinical research: guidelines for eliciting, recording, and quantifying mismatch negativity, P300, and N400.临床研究中的事件相关电位:诱发、记录和量化失配负波、P300和N400的指南。
Clin Neurophysiol. 2009 Nov;120(11):1883-1908. doi: 10.1016/j.clinph.2009.07.045. Epub 2009 Sep 30.
2
A new method for off-line removal of ocular artifact.一种用于离线去除眼电伪迹的新方法。
Electroencephalogr Clin Neurophysiol. 1983 Apr;55(4):468-84. doi: 10.1016/0013-4694(83)90135-9.
3
The positive and negative syndrome scale (PANSS) for schizophrenia.
精神分裂症的阳性与阴性症状量表(PANSS)
Schizophr Bull. 1987;13(2):261-76. doi: 10.1093/schbul/13.2.261.